Search for dissertations about: "collateral sensitivity"

Found 5 swedish dissertations containing the words collateral sensitivity.

2. 1. Peptidergic innervation of periarticular tissue : a study in the rat

   Author : Paul Ackermann; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Immunohistochemistry; radioimmunoassay; pain measurement; Achilles tendon; collateral ligaments; joint capsules; tendon rupture; regeneration; peripheral nervous system; neuropeptides; delta opioid receptor;

   Abstract : Painful musculo-skeletal disorders pose a tremendous burden on the healthcare system, the main reason being the limited knowledge of the underlying pathomechanisms and lack of specific treatment. Hypothetically, the peripheral nervous system in the musculo-skeletal tissues plays an important role in the regulation of pain, inflammation, vasoactivity and also tissue repair. READ MORE

4. 2. Ultrasonography of the hand

   Author : Margaretha Höglund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Extremities; hand; joint ligaments; injuries; ganglion; soft tissue neoplasm ultrasound; statistics.;

   Abstract : Purpose: A joint project of the Departments of Hand Surgery and Radiology at the same hospital in Stockholm to place during eight years from 1989 to 1996. The aim of the project was to evaluate the possible benefits of diagnostic ultrasound in connection with specific clinical problems in hand surgery. READ MORE

5. 3. Pharmacological and molecular investigations on the mechanisms underlying resistance of human leukaemia cells to the antimetabolites methotrexate, 6-mercaptopurine and 6-thioguanine

   Author : Alan Kambiz Fotoohi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The goal of this thesis has been to elucidate the mechanisms underlying resistance to methotrexate (MTX), 6-mercaptopurine (6-MP) and 6-thioguanine (6-TG), the antimetabolites widely used in treatment of childhood leukemia, as well as to determine the influence of 7-hydroxymethotrexate (7-OHMTX), the major metabolite of MTX, on the therapeutic action of MTX. Resistant sublines of leukemic cell lines were developed by long-term exposure to stepwise increasing concentrations of these different agents. READ MORE

6. 4. Interaction of cyclotides and bacteria : A study of the cyclotide action and the bacterial reaction

   Author : Sohaib Zafar Malik; Ulf Göransson; Dan Andersson; William Shafer; Uppsala universitet; []
   Keywords : Cyclotides; cycloviolacin O2; cycloviolacin O3; cycloviolacin O19; antimicrobial peptide resistance; Salmonella enterica; Eschericia coli; Viola odorata; Farmakognosi; Pharmacognosy;

   Abstract : The growing problem of antibiotic resistance and the lack of promising prospective antibiotics have forced us to search for new classes of antibiotics. Among the candidates to develop into future antibacterials are antimicrobial peptides (AMPs). READ MORE

7. 5. Operational Military Violence : A Cartography of Bureaucratic Minds and Practices

   Author : Anders Malm; Marie Demker; Dan Öberg; Annika Bergman-Rosamond; Försvarshögskolan; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; military violence; bureaucratisation; operational level; targeting; military masculinity; Krigsvetenskap; Krigsvetenskap; military violence; bureaucratisation; operational level; targeting; military masculinity;

   Abstract : Western use of military violence is becoming increasingly centralised, partly through the use of Unmanned Aerial Vehicles (or more commonly referred to as “drones” in the literature). Drone technology allows control and command of military operations to be put under one roof, and as military organisations traditionally have a close dependence on technological developments, procedures and regulations for centralised command and control have developed in close concert with advances in drone technology. READ MORE