Search for dissertations about: "colon cancer registry"

Showing result 1 - 5 of 19 swedish dissertations containing the words colon cancer registry.

2. 1. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer

   Author : Kajsa Ericson Lindquist; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; cancerology; Cytologi; onkologi; cancer; Multiple Tumors; Hereditary Nonpolyposis Colorectal Cancer; Cytology; Cohort study; Population based; Familial Risk of Cancer; Immunohistochemistry; MSH2; MSH6; MLH1; Microsatellite Instability; Soft Tissue Sarcomas; Cancer of the Upper Urinary Tract; Cancer of the Small Intestine; Colorectal Cancer;

   Abstract : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. READ MORE

4. 2. Colon Cancer, Prognosis After Surgery : What Are the Risks of Recurrent Disease, and How Do We Find Those at Risk?

   Author : Erik Osterman; Tobias Sjöblom; Bengt Glimelius; Lars Karlsson; Mats Hellström; Ismail Gögenur; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer; recurrence risk; prediction model; biomarkers; Oncology; Onkologi; Surgery; Kirurgi;

   Abstract : Colon cancer is the fourth most common cancer worldwide with approximately 1.2 million yearly cases. Developments in the standard of care have improved prognosis. In Paper I the recurrence risk was investigated in a national material consisting of 14,325 colon cancer patients. READ MORE

5. 3. Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker

   Author : Elinor Bexe-Lindskog; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; thymidine phosphorylase; chemotherapy; adjuvant; biological markers; prognosis; practice guidelines; radiotherapy;

   Abstract : Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the gene expression of the enzyme thymidine phosphorylase (TP), which was related to prognostic factors (paper I, n=254), evaluated as a predictive factor (paper III, n=125), and assessed by change of treatment (paper II, n=28). READ MORE

6. 4. Emergent colon cancer and postoperative complications - risks and management

   Author : Örvar Arnarson; Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; postoperative complications; bridge to surgery; emergency surgery; surgical specialization; Cancer registry;

   Abstract : Background:Colorectal cancer in the third most diagnosed cancer in Sweden and the second most common cause of cancer-related death in Sweden and worldwide. 10-30% of the cases present as emergencies, of which 80% are caused by large bowel obstruction (LBO). READ MORE

7. 5. Nutrition and colorectal cancer - The role of BMI, sex, biomarkers and dietary index

   Author : Alexandra Vulcan; Internmedicin - epidemiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kolrektal cancer; nutrition; fiber; kött; kostindex; CDQI; glukos; insulin; MKC;

   Abstract : Colorectal cancer (CRC) is one of the most common forms of cancer. The cause of CRC is multifactorial, and lifestyle factors are thought to be a major contributor to the development of CRC. READ MORE