Search for dissertations about: "combat survival"

Showing result 21 - 25 of 32 swedish dissertations containing the words combat survival.

  2. 21. Hormone-Sensitive Lipase - New roles in adipose tissue biology

    Author : Kristoffer Ström; Molekylär endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinoid; adipogenesis; adipocyte determination; HSL; WAT;

    Abstract : Obesity is defined as abnormal or excessive fat accumulation that may impair health, and increased knowledge about the enzymes controlling lipid metabolism is of great importance in order to combat this disease. Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from acylglycerols in adipocytes, but also plays important roles in other cell types. READ MORE

  4. 22. On aging and the role of Ubp3 in heterochromatic gene silencing and protein quality control

    Author : David Öling; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Aging; Protein damage; Segregation; Transcriptional silencing; rDNA; UBP3; SIR2; Protein aggregates;

    Abstract : Aging is characterized by a build-up of damage in organisms ranging from protists to multi-cellular species. This damage adversely affects core components such as DNA and proteins which are necessary to sustain life. READ MORE

  5. 23. Vascular development and safeguard mechanisms against tumorigenesis : oncogene-induced apoptosis and cellular senescence

    Author : Eduar Hejll; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angiogenesis;

    Abstract : Angiogenesis, apoptosis and senescence are all cellular processes that have an impact on tumor development. Angiogenesis or the new vessel formation from pre-existing ones is known to be required for invasive tumor growth and metastasis. READ MORE

  6. 24. Symbiotic and pathogenic factors in plant-microbe interaction: Structural basis of C-glycoside metabolism and lipoprotein transport in bacteria

    Author : Valentina Furlanetto; Christina Divne; Mats Sandgren; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Plant-Bacteria Interaction; Symbiotic Communication; C-Glycosylated Compounds; Enzymatic Deglycosylation; Pathogenic Interactions; Lipoprotein Localization; Lol System; Biotechnology; Bioteknologi;

    Abstract : The communication between plants and bacteria involves a complex chemical signaling network that mediates responses to various biotic and abiotic stresses, as well as establishing symbiotic relationships between different organisms.The first part of the thesis focuses on a mechanism for symbiotic communication between plants and bacteria and more specifically on how C-glycosylated aromatic polyketide compounds produced by plants can be used as a mechanism for plants to communicate with beneficial bacteria. READ MORE

  7. 25. Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246

    Author : Sophia Ceder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities that contribute to tumor growth. READ MORE