Search for dissertations about: "combinatorial chemistry"
Showing result 1 - 5 of 25 swedish dissertations containing the words combinatorial chemistry.
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1. Dynamic Sulfur Chemistry : Screening, Evaluation and Catalysis
Abstract : This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions. In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. READ MORE
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2. Discovery-Oriented Screening of Dynamic Systems: Combinatorial and Synthetic Applications
Abstract : This thesis is divided into six parts, all centered around the development of dynamic (i.e., reversibly interacting) systems of molecules and their applications in dynamic combinatorial chemistry (DCC) and organic synthesis. READ MORE
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3. Catalysis in Dynamic Systems: Control within Molecular Reaction Networks
Abstract : Life as we know it is based on complex networks of biochemical reactions that constantly interact within large dynamic systems. The field of systems chemistry uses chemical models to study how reaction networks – and thereby life – function on a molecular level. READ MORE
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4. Combinatorial Synthesis of Pilicides
Abstract : This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i. READ MORE
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5. Fast Chemistry by Microwave Heating : First Descriptions of Highly Enantioselective Microwave Protocols for Metal Catalysis; First Descriptions of in-situ Gas Generation for Fast Combinatorial Microwave Chemistry
Abstract : Microwave heating was applied to different palladium-catalyzed allylic substitution reactions. The use of various nucleophiles demonstrated C-, N-, O- and S- nucleophilicity. High yields and stereopurities of the corresponding alkyls, amides, ethers and sulfones were afforded after only 30 – 120 s of heating. READ MORE