Search for dissertations about: "complement C5"
Showing result 1 - 5 of 14 swedish dissertations containing the words complement C5.
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1. Complement-dependent defence against bacterial infection. Studies in C2 deficiency
Abstract : The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. READ MORE
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2. Glial cell responses, complement and clusterin expression after lesions in central or peripheral nervous system
Abstract : The present Thesis examines the expression and role of complement and the complement regulator clusterin after central or peripheral axon injury in relation to the responses of non-neuronal cells. Following peripheral sensory nerve injury, complement was expressed in the spinal cord and brain stem in association with reactive microglia, which also appeared to be a local source of complement. READ MORE
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3. Complement evasion strategies of human pathogens - the evolutionary arms race
Abstract : Although the complement system, a pivotal component of innate immunty, is centrally involved in host defense against pathogens, its overactivation or deregulation may excessively amplify inflammation and contribute to immunopathology. Periodontitis, an oral infection-driven chronic inflammatory disease, has been linked with complement disruption by periodontal bacteria, resulting in inflammation and pathogenesis. READ MORE
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4. The Role of Fc Gamma Receptors in Experimental Arthritis
Abstract : Induction of collagen-induced arthritis (CIA), an animal model for human rheumatoid arthritis, is dependent on anti-collagen type II (CII) antibodies. The effector mechanism by which autoantibodies contribute to inflammatory reactions in autoimmune diseases is not well understood. READ MORE
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5. Utilizing Solid Phase Cloning, Surface Display And Epitope Information for Antibody Generation and Characterization
Abstract : Antibodies have become indispensable tools in diagnostics, research and as therapeutics. There are several strategies to generate monoclonal antibodies (mAbs) in order to avoid the drawbacks of polyclonal antibodies (pAbs) for therapeutic use. READ MORE