Search for dissertations about: "complement receptors"
Showing result 1 - 5 of 67 swedish dissertations containing the words complement receptors.
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1. The Role of IgM and Complement in Antibody Responses
Abstract : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. READ MORE
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2. Feedback Enhancement of Antibody Responses via Complement and Fc Receptors
Abstract : IgG, IgM and IgE in complex with antigen have the capacity to regulate specific immune responses. In this investigation, the role of Fc receptors for IgG (FcγRI, FcγRII and FcγRIII) and complement receptors 1 and 2 (CR1/2) for antibody-mediated enhancement of antibody responses are investigated. READ MORE
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3. Antibody Feedback Regulation and T Cells
Abstract : Antibodies, passively administered or actively produced, regulate immune responses to the antigen they recognize. This phenomenon is called antibody-mediated feedback regulation. Feedback regulation can be positive or negative, resulting in >1000-fold enhancement or >99% suppression of the specific antibody response. READ MORE
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4. The Role of Fc Gamma Receptors in Experimental Arthritis
Abstract : Induction of collagen-induced arthritis (CIA), an animal model for human rheumatoid arthritis, is dependent on anti-collagen type II (CII) antibodies. The effector mechanism by which autoantibodies contribute to inflammatory reactions in autoimmune diseases is not well understood. READ MORE
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5. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis
Abstract : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms. However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. READ MORE