Search for dissertations about: "complement"

Showing result 6 - 10 of 973 swedish dissertations containing the word complement.

  1. 6. Complement aberrations and autoantibodies to complement proteins in relation to disease mechanisms

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Lillemor Melander Skattum; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C3 nephritic factors; GM allotypes; C1q autoantibodies; serum bactericidal activity; Neisseria meningitidis; idiopathic sudden hearing loss; complement; Acute poststreptococcal glomerulonephritis;

    Abstract : The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). READ MORE

  2. 7. The complement system in stherosclerosis and arthritis

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Linda Persson; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement; C3; factor B; ASP; atherosclerosis; hyperlipidemia; arthritis;

    Abstract : The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, neutralization of pathogens, regulation of antibody responses and disruption of cell membranes. READ MORE

  3. 8. Crosstalk Between Activated Platelets and the Complement System

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Osama A. Hamad; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Abstract : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. READ MORE

  4. 9. Synaptic elimination and the complement system in Alzhaimer's disease

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jonny Daborg; Göteborgs universitet.; Gothenburg University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synapse; Alzheimer s disease; Genetics; CSF; Complement; RAGE;

    Abstract : The mechanisms behind Alzheimer’s disease (AD) are largely unknown. The disease is to a large extent hereditary, and the best pathophysiological correlate to the severity of the symptoms is loss of synapses. READ MORE

  5. 10. Effects of Complement Opsonization of HIV on Dendritic Cells and Implications for the Immune Response

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Rada Ellegård; Linköpings universitet.; Linköpings universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE