Search for dissertations about: "complex diseases"

Showing result 1 - 5 of 655 swedish dissertations containing the words complex diseases.

  1. 1. Immune Complex Regulated Cytokine Production in Rheumatic and Lymphoproliferative Diseases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Linda Mathsson; Uppsala universitet.; [2007]
    Keywords : Immunology; Immune complex; Cytokines; Rheumatic diseases; Lymphoproliferative diseases; Immunologi;

    Abstract : Immune complexes (ICs) are produced during normal immune responses and facilitate clearance of foreign antigens. ICs not efficiently cleared from the circulation can cause tissue damage. This might happen if ICs are formed with autoantibodies and autoantigens. READ MORE

  2. 2. Strategies for Identification of Susceptibility Genes in Complex Autoimmune Diseases

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ludmila Prokunina; Uppsala universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; complex diseases; autoimmune diseases; genetic mapping; functional studies; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik;

    Abstract : Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are complex autoimmune diseases affecting 0.05-2% of the population worldwide. Genetic studies detected linkage with SLE in the 2q37 region, and intensive family-based and case-control association studies in several populations identified that allele A of the SNP PD-1. READ MORE

  3. 3. Genetics of complex disease

    University dissertation from Lund University, Faculty of Science, Department of Biology

    Author : Viktor Henmyr; Lund University.; Lunds universitet.; [2017-09]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; complex disease; allergic rhinitis; Chronic rhinosinusitis; genetics; associations; GWAS; resequencing;

    Abstract : To find true genetic associations in complex diseases, such as allergic rhinitis and chronic rhinosinusitis, is a difficult task. Both are polygenetic diseases where it is believed that genetic variation in several genes make up their phenotypes. READ MORE

  4. 4. Mass Spectrometry of Non-protein Amino Acids BMAA and Neurodegenerative Diseases

    University dissertation from Stockholm : Department of Environmental Science and Analytical Chemistry, Stockholm University

    Author : Liying Jiang; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurodegenerative diseases; BMAA; Isomers; LC-MS MS; Cyanobacteria; Diatoms; Seafood contamination; Analytical Chemistry; analytisk kemi;

    Abstract : Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. READ MORE

  5. 5. Novel strategies to explore The complex genetics of autoimmune diseases

    University dissertation from Medical Inflammation Research, Department of Experimental Medicine, Faculty of Medicine, Lund University

    Author : Martina Johannesson; Lund University.; Lunds universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunology; serology; Immunologi; serologi; cytogenetik; Genetik; cytogenetics; Genetics; collagen induced arthritis; QTL mapping; complex traits; autoimmunity; genetics;

    Abstract : Autoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. READ MORE