Search for dissertations about: "complexed PSA"

Found 4 swedish dissertations containing the words complexed PSA.

  1. 1. The Kallikrein-Related Peptidases hK2 and PSA with Emphasis on Genetic Variation, Secretion, and Sperm Motility

    University dissertation from Lund University

    Author : Charlotta Sävblom; Lund University.; Lunds universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human glandular kallikrein 2; KLK3; hk2; prostate-specific antigen; PSA; sperm motility; seminal plasma; androgen receptor; SNP; CAG; KLK2;

    Abstract : Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are secreted by the prostate into seminal plasma and through leakage into blood. This leakage increases rapidly in prostate disease, and PSA is used worldwide as a marker of prostate cancer. READ MORE

  2. 2. Metabolism of free and complexed prostate - specific antigen and their utility for diagnosis and prognosis of prostate cancer

    University dissertation from Department of Urology, Malmö University Hospital, 205 02 Malmö, Sweden

    Author : Thomas Björk; Lund University.; Lunds universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benign prostatic hyperplasia; alpha-1-antichymotrypsin; PSA; prostate cancer; prostate-specific antigen; Urology; nephrology; Urologi; nefrologi;

    Abstract : Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). READ MORE

  3. 3. Human glandular kallikrein 2 (hK2) in prostate cancer: Clinical and Methodological studies

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Charlotte Becker; Lund University.; Lunds universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; screening; prostate cancer; PSA; Human glandular kallikrein; hK2; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : Human glandular kallikrein 2 (hK2) is a predominantly prostate produced protein with many similarities to prostate-specific antigen (PSA). Just like for PSA elevated levels of hK2 can be found in men with protate cancer. We created an assay where hK2 in serum could reliably and with negligible cross-reactivity with PSA, be measured down to 0. READ MORE

  4. 4. Impact of renal dysfunction on serum Prostate-Specific Antigen

    University dissertation from Department of Nephrology and Transplantation, Lund University

    Author : Laila Bruun; Lund University.; Lunds universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; hK2; Urology; intra-individual variation; elimination; peritoneal dialysis; renal dysfunction; kidney transplantation; hemodialysis; nefrologi; nephrology; PSA;

    Abstract : Measurement of prostate-specific antigen (PSA) in blood is an important tool in detection for prostate cancer. PSA occurs in several molecular forms in blood: mainly as a free form with a molecular mass of 28 kDa; and as PSA complexed to alpha-1-antichymotrypsin, complexed PSA, with a molecular mass of 90 kDa. READ MORE