Search for dissertations about: "compound 48 80"

Showing result 1 - 5 of 14 swedish dissertations containing the words compound 48 80.

  1. 1. Peripheral Regulation of Pain and Itch

    Author : Elín Ingibjörg Magnúsdóttir; Malin C. Lagerström; George H. Caughey; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pain; itch; CGRP; TRPV1; mast cell; mast cell protease; mMCP4; mMCP6; CPA3; endothelin-1; compound 48 80; MRGPRX2; single-stranded oligonucleotide;

    Abstract : Pain and itch are diverse sensory modalities, transmitted by the somatosensory nervous system. Stimuli such as heat, cold, mechanical pain and itch can be transmitted by different neuronal populations, which show considerable overlap with regards to sensory activation. READ MORE

  2. 2. Developing otitis media : experimental studies in particular regarding inflammatory changes in the tympanic membrane

    Author : Per Olof Eriksson; Sten Hellström; Karin Prellner; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; otitis media with effusion; acute otitis media; myringotomy; tympanic membrane; rat; Streptococcus pneumoniae; compound 48 80; mast cell; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Abstract : Otitis media (OM), one of the commonest of childhood diseases, causes much suffering. OM exists in a variety of forms, two of which are acute otitis media (AOM) and otitis media with effusion (OME). READ MORE

  3. 3. Pharmacology of Palmitoylethanolamide and Related Compounds

    Author : Kent-Olov Jonsson; Christopher J Fowler; Gunnar Tiger; Andrew SC Rice; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anandamide; cannabinoid; FAAH; palmitoylethanolamide; palmitoylisopropylamide; inflammation; mast cells; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. READ MORE

  4. 4. Role of mast cell-derived mediators for leukocyte/endothelium-interactions and microvascular mechanisms in inflammation and in anaphylaxis

    Author : Yancai Guo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Anaphylaxis; histamine; intravital microscopy; leukocyte; mast cell-deficient rat Ws Ws ; microdialysis;

    Abstract : The overall objective of this thesis was to study the roles of mast cell-derived mediators for leukocyte/endothelium interactions and microvascular mechanisms in inflammation and in anaphylaxis, using mast cell-deficient Ws/Ws rats and their wild-type +/+ littermates. The efflux of endogenous histamine and edema formation evoked by subplantar injection of compound 48/80 in rat hindpaws was dose-dependent in +/+ rats, and was essentially lacking in Ws/Ws rats. READ MORE

  5. 5. Non-digestible Polysaccharides and Intestinal Barrier Function : specific focus on its efficacy in elderly and patients with Crohn’s disease

    Author : John-Peter Ganda Mall; Robert Jan Brummer; Ida Schoultz; Åsa Keita; Mikael Wirén; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Non-digestible polysachharides; beta-glucan; arabinoxylan; barrier function; permeability; Ussing chamber; elderly; Crohn’s disease;

    Abstract : A large number of elderly suffer from gastrointestinal (GI) symptoms such as constipation and diarrhoea. The underlying mechanisms of age-acquired GI symptoms are not well studied but are necessary to clarify in order to recommend the right treatment. READ MORE