Search for dissertations about: "computational proteomics"

Showing result 1 - 5 of 19 swedish dissertations containing the words computational proteomics.

  1. 1. A multivariate approach to computational molecular biology

    University dissertation from Umeå : Kemi

    Author : Fredrik Pettersson; Umeå universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PLS; PCA; biomarker; Drosophila; SNP; linkage; disequilibrium; bioinformatics; computational; molecular; biology; genomics; microarray; SELDI; proteomics; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Abstract : This thesis describes the application of multivariate methods in analyses of genomic DNA sequences, gene expression and protein synthesis, which represent each of the steps in the central dogma of biology. The recent finalisation of large sequencing projects has given us a definable core of genetic data and large-scale methods for the dynamic quantification of gene expression and protein synthesis. READ MORE

  2. 2. Computational methods for analysis of fragmented sequence data

    University dissertation from Göteborg : Chalmers University of Technology

    Author : Fredrik Boulund; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; metagenomics; proteomics; sequencing; distributed computing;

    Abstract : Recent developments in genomic and proteomic sequencing technologies haverevolutionized research in life sciences, providing new opportunities for thestudy of biological systems. However, modern sequence data sets are large,diverse, and heavily fragmented, which presents new challenges for theiranalysis and interpretation. READ MORE

  3. 3. The accuracy of statistical confidence estimates in shotgun proteomics

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Viktor Granholm; Stockholms universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteomics; Peptides; Statistics; Mass spectrometry; Tandem mass spectrometry; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : High-throughput techniques are currently some of the most promising methods to study molecular biology, with the potential to improve medicine and enable new biological applications. In proteomics, the large scale study of proteins, the leading method is mass spectrometry. READ MORE

  4. 4. Quantitative analysis of mass spectrometry proteomics data : Software for improved life science

    University dissertation from Lund University Press

    Author : Johan Teleman; [2016-05]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; computational proteomics; bioinformatics; life science; data complexity; algorithms; mass spectrometry;

    Abstract : The rapid advances in life science, including the sequencing of the human genome and numerous other techiques, has given an extraordinary ability to aquire data on biological systems and human disease. Even so, drug development costs are higher than ever, while the rate of new approved treatments is historically low. READ MORE

  5. 5. Computational analyses of biological sequences -applications to antibody-based proteomics and gene family characterization

    University dissertation from Stockholm : KTH

    Author : Mats Lindskog; KTH.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; antigen; antibodies; antibody-based proteomics; biocomputing; bioinformatics; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Abstract : Following the completion of the human genome sequence, post-genomic efforts have shifted the focus towards the analysis of the encoded proteome. Several different systematic proteomics approaches have emerged, for instance, antibody-based proteomics initiatives, where antibodies are used to functionally explore the human proteome. READ MORE