Search for dissertations about: "conformational analysis"

Showing result 1 - 5 of 115 swedish dissertations containing the words conformational analysis.

  1. 1. Assembling and Unraveling Carbohydrates Structures Conformational analysis of synthesized branched oligosaccharides

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Thibault Angles d'Ortoli; Stockholms universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Convergent carbohydrate synthesis; Super-armed donors; Glycosylation; Conformational analysis; NMR; Chemical shift prediction; Organic Chemistry; organisk kemi;

    Abstract : Advances in the elaboration of vaccines and enzyme inhibitors rely on acquiring more knowledge about protein-carbohydrate binding events. Furthermore, the relationships between biological function and the three-dimensional properties of large glycans can be studied by focusing on the structural components they contained, namely, by scaling down the system under analysis. READ MORE

  2. 2. Structural and Conformational Studies of Oligo- and Polysaccharides

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Mona Zaccheus; Stockholms universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; structural analysis; conformational analysis; carbohydrates; polysaccharides; Organic Chemistry; organisk kemi;

    Abstract : The focus of this thesis is to examine the structural properties of polysaccharides produced by bacteria, as well as the dynamic and conformational behavior of a synthetically derived oligosaccharide.The primary structures of the O-polysaccharide repeating units of four different Escherichia coli (E. READ MORE

  3. 3. Computational Analysis of Carbohydrates Dynamical Properties and Interactions

    University dissertation from Stockholm : Institutionen för organisk kemi

    Author : Robert Eklund; Stockholms universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate; DFT; ab initio; docking calculations; Molecular dynamics; Langevin Dynaimcs; structure analysis; carbohydrate-protein interaction; Chemical shift calculations; Spin spin coupling constants.; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : In this thesis a computational complement to experimental observables will be presented. Computational tools such as molecular dynamics and quantum chemical tools will be used to aid in the interpretation of experimentally (NMR) obtained structural data. READ MORE

  4. 4. Metallocene based peptidomimetics and chiral catalysts

    University dissertation from Organic Chemistry, Lund University

    Author : Suzana Maricic; Lunds universitet.; Lund University.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; asymmetric catalysis.; metallocene based amino alcohols; one-pot macrocyclisation; cyclic peptides; Organometallic substance P and Leu 5 -enkephalin; conformational analysis;

    Abstract : Popular Abstract in Swedish Ett antal optiskt aktiva metalloorganiska Phe-AAn-Phe subenheter har syntetiserats via intramolekulär cyklisering av motsvarande bis(aminosyra)derivat. Bis(aminosyra)derivaten var i sin tur erhållna från en förbättrad multistegssyntes, vars nyckelsteg är Horner-Wadswort-Emmons olefinering av metalloorganiska aldehyder med fosfonylglycin-reagens, enantioselektiv hydrogenering av didehydroaminosyror och klassisk lösnings- och/eller fastfas peptid syntetisk metodologi. READ MORE

  5. 5. Modulation of Molecular Properties Host–Guest Interactions for Structural Analysis and Chemical Reactions

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sara Norrehed; Uppsala universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; host-guest systems; conformational analysis; NMR spectroscopy; bispidines; porphyrins; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Abstract : This thesis concerns the construction, use and modulation of various host–guest systems, from small bispidines for binding of inorganic ions to bisporphyrin clips for supramolecular systems.Small flexible molecules undergo fast conformational movements when in solution. READ MORE