Search for dissertations about: "conformational analysis"

Showing result 1 - 5 of 118 swedish dissertations containing the words conformational analysis.

  1. 1. Assembling and Unraveling Carbohydrates Structures Conformational analysis of synthesized branched oligosaccharides

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Thibault Angles d'Ortoli; Göran Widmalm; Christian Marcus Pedersen; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Convergent carbohydrate synthesis; Super-armed donors; Glycosylation; Conformational analysis; NMR; Chemical shift prediction; Organic Chemistry; organisk kemi;

    Abstract : Advances in the elaboration of vaccines and enzyme inhibitors rely on acquiring more knowledge about protein-carbohydrate binding events. Furthermore, the relationships between biological function and the three-dimensional properties of large glycans can be studied by focusing on the structural components they contained, namely, by scaling down the system under analysis. READ MORE

  2. 2. Structural and Conformational Studies of Oligo- and Polysaccharides

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Mona Zaccheus; Göran Widmalm; Christina De Castro; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; structural analysis; conformational analysis; carbohydrates; polysaccharides; Organic Chemistry; organisk kemi;

    Abstract : The focus of this thesis is to examine the structural properties of polysaccharides produced by bacteria, as well as the dynamic and conformational behavior of a synthetically derived oligosaccharide.The primary structures of the O-polysaccharide repeating units of four different Escherichia coli (E. READ MORE

  3. 3. Computational Analysis of Carbohydrates Dynamical Properties and Interactions

    University dissertation from Stockholm : Institutionen för organisk kemi

    Author : Robert Eklund; Göran Widmalm; Sören B. Engelsen; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate; DFT; ab initio; docking calculations; Molecular dynamics; Langevin Dynaimcs; structure analysis; carbohydrate-protein interaction; Chemical shift calculations; Spin spin coupling constants.; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : In this thesis a computational complement to experimental observables will be presented. Computational tools such as molecular dynamics and quantum chemical tools will be used to aid in the interpretation of experimentally (NMR) obtained structural data. READ MORE

  4. 4. Light-Triggered Conformational Switches for Modulation of Molecular Recognition Applications for Peptidomimetics and Supramolecular Systems

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Blom; Adolf Gogoll; Morten Grötli; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bisporphyrin tweezers; peptidomimetics; host-guest systems; conformational analysis; supramolecular chemistry; photochemistry; Organisk kemi; Organic Chemistry; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Abstract : The main focus of this thesis is on photochemical modulation of molecular recognition in various host-guest systems. This involves the design, synthesis and integration of light-triggered conformational switches into peptidomimetic guests and molecular tweezer hosts. READ MORE

  5. 5. Modulation of Molecular Properties Host–Guest Interactions for Structural Analysis and Chemical Reactions

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sara Norrehed; Adolf Gogoll; Jerker Mårtensson; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; host-guest systems; conformational analysis; NMR spectroscopy; bispidines; porphyrins; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

    Abstract : This thesis concerns the construction, use and modulation of various host–guest systems, from small bispidines for binding of inorganic ions to bisporphyrin clips for supramolecular systems.Small flexible molecules undergo fast conformational movements when in solution. READ MORE