Search for dissertations about: "conformational analysis"
Showing result 21 - 25 of 145 swedish dissertations containing the words conformational analysis.
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21. Metallocene based peptidomimetics and chiral catalysts
Abstract : Several optically active organometallic Phe-AAn-Phe peptidomimetics and macrocyclic Phe-(Phe)n peptides have been synthesized by either intra- or intermolecular peptide bond formation of the corresponding bis(amino acid) derivatives. The key bis(amino acid) derivatives were available from an improved multi-step synthetic route, utilising Horner-Wadswort-Emmons olefination of organometallic aldehydes with phosphonylglycine reagents, enantioselective hydrogenation of didehydro amino acids and classical solution and/or solid phase peptide synthesis methodology. READ MORE
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22. Structural and Conformational Analysis of Bacterial Polysaccharides using NMR Spectroscopy
Abstract : Carbohydrates is one of the three classes of biomolecules found in nature. It is the most common one in comparison to the other two classes, lipids and proteins. However, this simple categorization does not reflect the reality since carbohydrates often are covalently linked to e.g. READ MORE
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23. Photoinduced Electron and Energy Transfer in Π-Conjugated Systems
Abstract : Photosynthesis is a fascinating process that provides food and oxygen. In this thesis, focus is on understanding and controlling the early processes of photosynthesis, namely photoinduced energy and electron transfer. READ MORE
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24. Applications of nuclear magnetic resonance spectroscopy in structural and conformational analysis
Abstract : .... READ MORE
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25. Computational Modeling of Macrocycles and Structure-Based Design of Novel Antibacterial Compounds
Abstract : The integration of computational methods into the drug discovery process provides valuable tools to help advance new and improved drugs into the clinic. As medicinal chemists explore novel targets and new areas of chemical space, our computational toolkit must also evolve. READ MORE