Search for dissertations about: "conformational strain"

Showing result 1 - 5 of 8 swedish dissertations containing the words conformational strain.

  1. 1. Autoproteolysis accelerated by conformational strain - a novel biochemical mechanism

    Author : Denny Johansson; Göteborgs universitet; []
    Keywords : SEA domain; autoproteolysis; MUC1; conformational strain; protein folding;

    Abstract : Natural fragmentation of polypeptide chains by autoproteolysis occurs in a number of protein families. It is a vital step in the maturation of several enzymes and in the formation of membrane-associated mucins that constitute a part of the protective mucus barrier lining epithelial cells. READ MORE

  2. 2. Computational analysis of oligosaccharide conformations – methodological development, applied studies, and design of glycomimetics

    Author : Francesco Strino; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histo-blood group antigens; Burkholderia cepacia; genetic algorithms; norovirus; selenoglycosides; sugar conformations; thioglycosides; saccharide conformations;

    Abstract : Carbohydrates are the most abundant class of biomolecules. Besides their roles as structural elements and energy storage, they are involved in signaling and recognition processes. Their functions and activities depend on their preferred conformations. READ MORE

  3. 3. Luminescent molecular recognition of pathognomonic and aging associated protein aggregates

    Author : Daniel Sjölander; Per Hammarström; Peter Nilsson; Uno Carlsson; Jan Johansson; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Various protein inclusions have been recognized to be associated with aging and pathogenic conditions, such as in Alzheimer’s disease, Parkinson’s disease, Type 2 diabetes, and the prionoses Creutzfeldt-Jakob disease, Chronic wasting disease (CWD), and Mad cow disease. The causative transition of protein aggregation is the alteration in the conformation of the protein that renders the protein susceptible towards self-assembly. READ MORE

  4. 4. RsbX and stress response in Listeria monocytogenes

    Author : Ana Henriques de Oliveira; Jörgen Johansson; Cormac Gahan; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; SigB; stressosome; RsbX; phosphorylation; growth; competitiveness; motility; energetic cost; homeostasis; stress response; virulence; invasion; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Abstract : Listeria monocytogenes is a ubiquitous foodborne Gram-positive bacterium. Despite being mainly a soil bacterium, it can reach the food processing environment and contaminate food destined for human consumption, causing outbreaks. READ MORE

  5. 5. Wood Hemicelluloses - Fundamental Insights on Biological and Technical Properties

    Author : Jennie Berglund; Mikael Lindström; Gunnar Henriksson; Francisco Vilaplana; Jakob Wohlert; Martin Lawoko; Maija Tenkanen; KTH; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; hemicellulose; wood; glucomannan; xylan; structure; acetylation; flexibility; solubility; interaction with cellulose; stability.; hemicellulosa; trä; glukomannan; xylan; struktur; acetylering; flexibilitet; löslighet; interaktion med cellulosa; stabilitet.; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Hemicelluloses are a group of heterogeneous polysaccharides representing around 30 % of wood where the dominating types are xylans, glucomannans and xyloglucans. Hemicelluloses complex molecular structure makes it difficult to understand the relationship between structure and properties entirely, and their biological role is not yet fully verified. READ MORE