Search for dissertations about: "congenital malformation"

Showing result 1 - 5 of 38 swedish dissertations containing the words congenital malformation.

  2. 1. Maternal smoking and congenital malformations

    Author : Karin Källén; Tornbladinstitutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratologi; Utvecklingsbiologi; embryology human ; ontogeny; Epidemiology; smoking; malformation; pregnancy; registry; confounders; teratology; Development biology; embryologi människa ;

    Abstract : About two percent of Swedish newborn infants are born with a significant congenital malformations which is reported to the Swedish Registry of Congenital Malformations (RCM), and/or the Swedish Medical Birth Registry (MBR). In spite of persistent public health recommendations, about 16% of the Swedish pregnant women are smoking during pregnancy (1996). READ MORE

  4. 2. Role of embryonic mitochondria in the generation of congenital malformations in diabetic pregnancy

    Author : Xiaolin Yang; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; embryo; diabetic pregnancy; congenital malformation; mitochondria; high-amplitudemitochondrial swelling; oxygen uptake; glucose utilization; Crabtree effect; superoxide generation; antioxidant; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Diabetic pregnancy is associated with an increased incidence of congenital malformations. The teratologicalmechanism may be related to an alteration of embryonic organogenesis by maternal metabolic derangementsduring early gestation. READ MORE

  5. 3. 12-14 week scan with emphasis on risk assessment for fetal structural malformations and fetal loss

    Author : Maria-Dorothea Westin; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; reproduction; sexuality; Obstetrics; gynaecology; andrology; Miscarriage; Malformation; Congenital cardiac defect; Nuchal translucency; Prenatal diagnosis; Medicin människa och djur ; Medicine human and vertebrates ; Risk assessment;

    Abstract : The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. READ MORE

  6. 4. Developmental disturbances of the embryo in diabetic pregnancy

    Author : Parri Wentzel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; pregnancy; embryo; malformation; glucose; ROS; SOD; NAC; prosta- glandin; COX; COX inhibitor; gene expression; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Maternal diabetes during pregnancy constitutes an increased risk for congenital malformation in the offspring. Previous studies have suggested that diabetic embryopathy is associated with an excess of reactive oxygen species (ROS) as well as with a disturbance of prostaglandin (PG) metabolism. READ MORE

  7. 5. Molecular Characterisation of Structural Chromosomal Abnormalities Associated with Congenital Disorders

    Author : Mahmoud R. Mansouri; Niklas Dahl; Hans Van Bokhoven; Uppsala universitet; []
    Keywords : Genetics; Chromosomal abnormalities; Mental retardation; Hypospadias and anal malformation; Premature ovarian failure; Autism; Array-CGH; ZDHHC15; Genetik;

    Abstract : Chromosomal abnormalities are defined as changes in the chromosome structure and fall in one of two categories. The first category is numerical alterations while the second category consists of structural abnormalities. Structural chromosomal abnormalities do not always interrupt genes in order to cause disease. READ MORE