Search for dissertations about: "conjugate addition"
Showing result 21 - 25 of 50 swedish dissertations containing the words conjugate addition.
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21. Approaches to accelerate methods for solving systems of equations arising in nonlinear optimization
Abstract : Methods for solving nonlinear optimization problems typically involve solving systems of equations. This thesis concerns approaches for accelerating some of those methods. In our setting, accelerating involves finding a trade-off between the computational cost of an iteration and the quality of the computed search direction. READ MORE
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22. Drug Eluting Hydrogels : Design, Synthesis and Evaluation
Abstract : Hydrogels have successfully proved themselves useful for drug delivery applications and several delivery routes have been developed over the years. The particular interest in this work was to design, synthesise and evaluate in situ forming drug eluting hydrogels, which have the potential to ameliorate the healing of cardiovascular diseases. READ MORE
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23. Vascular Interactions in Innate Immunity and Immunothrombosis: : Models of Endothelial Protection
Abstract : The phenomenon known as immunothrombosis has garnered increased attention over the last few years. Much work has been done to characterize the cross talk between hemostasis and the innate immune system. READ MORE
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24. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization
Abstract : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. READ MORE
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25. Salinomycin analogs : Mechanistic probes and structure–activity relationships against cancer stem cells
Abstract : Cancer stem cells are a subpopulation of cells that possess an increased tumorigenic potential. Such cells are connected to drug resistance, metastasis, and cancer recurrence. In 2009, the polyether ionophore salinomycin was shown to exhibit selective activity against cancer stem cells. READ MORE