Search for dissertations about: "conjugation"

Showing result 6 - 10 of 210 swedish dissertations containing the word conjugation.

  2. 6. Heavy-Core Staffanes : A Computational Study of Their Fundamental Properties of Interest for Molecular Electronics

    Author : Niclas Sandström; Henrik Ottosson; Leif Hammarström; Bo Albinsson; Uppsala universitet; []
    Keywords : Organic chemistry; conjugation; polarizability; Group 14 elements; cage compounds; electronic excitations; quantum chemistry; molecular electronics; Organisk kemi;

    Abstract : The basic building blocks in molecular electronics often correspond to conjugated molecules. A compound class consisting of rigid rod-like staffane molecules with the heavier Group 14 elements Si, Ge, Sn and Pb at their bridgehead positions has now been investigated. READ MORE

  4. 7. Investigations of chemical and enzymatic functionalization of affinity proteins

    Author : Anders Myrhammar; Amelie Eriksson Karlström; Per-Åke Nygren; Christian Heinis; KTH; []
    Keywords : Affinity protein; affibody; conjugation; solid phase peptide synthesis; proteolytic stability; peptide nucleic acid PNA .; Bioteknologi; Biotechnology;

    Abstract : AbstractAffinity proteins are important reagents in research, diagnostics and therapeutic settings. The focus of this thesis has been on investigating different chemical and enzymatic strategies for engineering of affinity proteins to generate affinity reagents with improved or changed functionality. READ MORE

  5. 8. Characterization of conjugated protease inhibitors

    Author : Erika Billinger; Gunnar Johansson; Boris Turk; Uppsala universitet; []
    Keywords : Serine protease inhibitors; conjugation; immobilization; leupeptin analogues; potato serine protease inhibitor; soluble carriers; inorganic carriers.; Biokemi; Biochemistry;

    Abstract : The overall theme of this thesis is a step by step approach for the design and characterization of conjugated protease inhibitors. This involves both a new assay method for protease activity and protease inhibition (paper I), a study of the stoichiometry for protease inhibitor interaction (paper II), design of inhibitory peptides (paper IV) and the construction of inhibitor conjugates (paper III & IV). READ MORE

  6. 9. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides

    Author : Jianhui Rong; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; 2-O-sulphotransferase; neo-glycosaminoglycan; conjugation; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. READ MORE

  7. 10. Exploring the mechanistic details of Gram-positive Type 4 Secretion Systems

    Author : Lena Lassinantti; Ronnie Berntsson; A. Elisabeth Sauer-Eriksson; Sjoerd Wanrooij; Samuel Wagner; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial resistance; Horizontal gene transfer; Gram-positive bacteria; Type 4 Secretion Systems; Conjugation; Enterococcus faecalis; pCF10; PrgU; PcfF; PrgB; Biochemistry; biokemi;

    Abstract : Hospital acquired (i.e. nosocomial) infections and antibiotic resistance are large issues in the world today, with about 1.3 million people estimated to have died from antibiotic resistant infections in 2019 alone, and these problems are on the rise. READ MORE