Search for dissertations about: "continuous infusion"

Showing result 1 - 5 of 65 swedish dissertations containing the words continuous infusion.

  1. 1. Pharmacotherapy for Parkinson's Disease - Observations and Innovations

    Author : Dag Nyholm; Sten-Magnus Aquilonius; Andrew Lees; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Parkinson s disease; levodopa; pharmacokinetics; infusion; drug delivery systems; electronic patient diary; Neurovetenskap; Neurology; Neurologi; Neurology; Neurologi;

    Abstract : Pharmacotherapy for Parkinson’s disease (PD) is based on levodopa, the most effective dopaminergic drug. The development of motor complications constitutes the major challenge for new or refined therapies. READ MORE

  2. 2. Automating levodopa dosing schedules for Parkinson’s disease

    Author : Ilias Thomas; Jerker Westin; Moudud Alam; Björn Eskofier; Högskolan Dalarna; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Parkinson’s disease; levodopa; symptom assessment; symptom management; dosing algorithms; wearable sensors; microtablets; continuous infusion; FLOAT - Flexible Levodopa Optimizing Assistive Technology; FLOAT - Flexibel levodopa-optimerings och individanpassningsteknik;

    Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disease. Levodopa is mainly used to manage the motor symptoms of PD. However, disease progression and long-term use of levodopa cause reduced medication efficacy and side effects. When that happens, precise individualized dosing schedules are required. READ MORE

  3. 3. New Approaches for Levodopa Treatment in Parkinson’s Disease

    Author : Marina Senek; Dag Nyholm; Elisabet I Nielsen; Maral Mouradian; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; Pharmacokinetics; Pharmacodynamics; Population modeling; Levodopa; Carbidopa; Entacapone; Microtablets; Intestinal infusion;

    Abstract : Parkinson’s disease (PD) is characterized by degeneration of dopaminergic cells, which results in dopamine depletion. Levodopa is the most effective symptomatic treatment, however, disease progression along with the unfavorable pharmacokinetics of levodopa makes the disease increasingly difficult to treat with time. READ MORE

  4. 4. Risk Factors for Diabetic Ketoacidosis in Children

    Author : Johan H Wersäll; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetic ketoacidosis; Type 1 diabetes; Continuous subcutaneous insulin infusion; Multiple daily injections; Cerebral edema; Socioeconomic status; Low economic standard; Level of education;

    Abstract : Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. It is preventable if timely administration of sufficient amounts of insulin is initiated. A large proportion of children are affected by DKA annually, especially at onset of type 1 diabetes (T1D). READ MORE

  5. 5. Assessment of cerebrospinal fluid system dynamics : novel infusion protocol, mathematical modelling and parameter estimation for hydrocephalus investigations

    Author : Kennet Andersson; Anders Eklund; Karin Wårdell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknik; hydrocefalus; infusionstest; utflödeskonduktans; systemidentifiering; Medical technology; Medicinsk teknik;

    Abstract : Patients with idiopathic normal pressure hydrocephalus (INPH) have a disturbance in the cerebrospinal fluid (CSF) system. The treatment is neurosurgical – a shunt is placed in the CSF system. The infusion test is used to assess CSF system dynamics and to aid in the selection of patients that will benefit from shunt surgery. READ MORE