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Showing result 1 - 5 of 86 swedish dissertations matching the above criteria.

  1. 1. Levosimendan in early experimental sepsis: effects on the heart and hepatosplanchnic circulation

    Author : Doris Cunha Goncalves; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; septic shock; myocardial oxygen consumption; myocardial dysfunction; levosimendan; endotoxin; contractility; catecholamines; calcium sensitizer; cardiotonic agents; splanchnic perfusion;

    Abstract : Sepsis-related cardiovascular dysfunction associated with fluid-unresponsive tissue hypoperfusion might require inotropic treatment. This cardiovascular dysfunction seems to involve calcium desensitization and adrenergic unresponsiveness. READ MORE

  2. 2. New insight into myocardin regulation and function in smooth muscle cells

    Author : Li Liu; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Contractility; Inflammation; Muscarinic receptor; Myocardin-related transcription factors; Phenotypic modulation; Smooth muscle; SRF; WWTR1; YAP1;

    Abstract : Smooth muscle cells (SMCs) are constituents of hollow inner organs. Their contractile function governs essential physiological functions, such as breathing, eating, blood pressure control, urination, and childbirth. READ MORE

  3. 3. On angiotensin II receptor type 2 receptors in the small intestine

    Author : Sara Ewert; Göteborgs universitet; []
    Keywords : renin-angiotensin; angiotensin; small intestine; mucosa; epithelium; AT1; AT2; bradykinin; BK2 receptor; nitric oxide; iNOS; smooth muscle; contractility;

    Abstract : The endocrine renin-angiotensin system (RAS) is important in the regulation of extracellular fluid volume and systemic blood pressure in strenuous conditions such as hypovolemia. Also present locally in peripheral tissues, all components of RAS are expressed and have been shown to modulate development, cell growth and inflammation. READ MORE

  4. 4. Left ventricular function's relation to load, experimental studies in a porcine model

    Author : Roman A'roch; Michael Haney; Jan Poelaert; Lars-Åke Brodin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heart function; preload; afterload; contractility; myocardial tissue velocity; speckle tracking; Anaesthetics and intensive care; Anestesiologi och intensivvård; Cardiology; kardiologi;

    Abstract : Background: Loading conditions are recognized to influence ventricular function according to the Starling relationship for length/stretch and force.  Many modern echocardiographic parameters which have been announced as describing ventricular function and contractile status, may be confounded by uncontrolled and unmeasured load. READ MORE

  5. 5. The Nitric Oxide and Renin-angiotensin II Systems in the Human Esophagus

    Author : Anna Casselbrant; Göteborgs universitet; []
    Keywords : Acid; nitric oxide; nitric oxide synthase; salivary secretion; renin-angiotensin; At1 receptor; AT2 receptor; mucosa; smooth muscle; contractility; peristaltic; high-pressure zone;

    Abstract : .... READ MORE