Search for dissertations about: "contralateral breast cancer"

Showing result 1 - 5 of 12 swedish dissertations containing the words contralateral breast cancer.

2. 1. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer

   Author : Sara Alkner; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; prognosis; treatment prediction; endocrine treatment; tamoxifen; coactivator; AIB1; PAX2; SRC; contralateral breast cancer; premenopausal; randomized trial; mode of detection; mammography.;

   Abstract : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. READ MORE

4. 2. Breast cancer in young women. Aspects of heredity and contralateral disease

   Author : Annelie Augustinsson; LUCC: Lunds universitets cancercentrum; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Early-onset; Genetic counseling; Genetic testing; BRCA1 and BRCA2; Contralateral breast cancer; Breast cancer; Early-onset; Genetic counseling; Genetic testing; BRCA1 and BRCA2; Contralateral breast cancer;

   Abstract : Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. READ MORE

5. 3. Long-term effects of adjuvant tamoxifen treatment on cardiovascular disease and cancer

   Author : Johan Rosell; John Carstensen; Olle Stål; Bo Nordenskjöld; Lars Holmberg; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adjuvant; adverse events; breast cancer; cerebrovascular disease; coronary heart disease; heart failure; lung cancer; second primary cancer; tamoxifen;

   Abstract : The aims of this thesis were to investigate the long-term effects of adjuvant tamoxifen treatment on breast cancer recurrence and mortality, cardiovascular disease, and the incidence of secondary cancer.Between 1982 and 1992, postmenopausal patients with early stage breast cancer were included in a randomized clinical study of 2 or 5 years of postoperative tamoxifen therapy. READ MORE

6. 4. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing

   Author : Malin Dahlgren; Translational Oncogenomics; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; DNA sequencing; RNA sequencing; Metastasis; Biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2; Breast cancer; DNA sequencing; RNA sequencing; metastasis; biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2;

   Abstract : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. READ MORE

7. 5. The Value of Preoperative MRI in Breast Cancer Treatment

   Author : Virginia Gonzalez; Staffan Eriksson; Sophia Zackrissson; Uppsala universitet; []
   Keywords : preoperative breast MRI; breast cancer; breast-conserving surgery; Surgery; Kirurgi; Oncology; Onkologi; Radiology; Radiologi;

   Abstract : Breast magnetic resonance imaging (MRI) remains controversial as an image adjunct in preoperative settings in terms of short-term benefits and there are no survival data from randomized studies. This prospective, randomized, multicentre study included 440 patients (age ≤ 56 y) with breast cancer from three large-volume Swedish breast clinics. READ MORE