Search for dissertations about: "copd phenotype"

Showing result 1 - 5 of 13 swedish dissertations containing the words copd phenotype.

  2. 1. Epigenetic changes and immunological features of chronic obstructive pulmonary disease

    Author : Jonas Eriksson Ström; Annelie F. Behndig; Anders Bucht; Anne Lindberg; Erik Melén; Fabbri Leonardo M.; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; COPD; immunology; epigenetics; KOLIN; lungmedicin; Lung Medicine; immunologi; Immunology; medicinsk genetik; Medical Genetics;

    Abstract : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. READ MORE

  4. 2. Airway mechanics of mice and men

    Author : Lennart Lundblad; Malmö Klinisk fysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; radiologi; tomografi; tomography; medical instrumentation; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; Penh; emphysema; airway resistance; gas conditioning; plethysmography; lung mechanics; Boyle s law; Physiology; medicinsk instrumentering; Klinisk fysiologi; radiology; enhanced pause; pulmonary fibrosis; micro computed tomography; forced oscillation technique; COPD;

    Abstract : In this thesis we explore and further develop several techniques used in the animal laboratory as well as in the clinical setting. In particular, we expand the understanding and usefulness of plethysmographic techniques in small rodents. READ MORE

  5. 3. The Role of FCGBP in Mucus - Structure, Processing and Function

    Author : Erik Ehrencrona; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Abstract : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. READ MORE

  6. 4. On airway host defence during allergic inflammation

    Author : Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Keywords : Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Abstract : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. READ MORE

  7. 5. New Aspects of Alveolar Adaptive Immune Responses in COPD

    Author : Michiko Mori; Luftvägsinflammation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Chronic obstructive pulmonary disease (COPD) is characterised by a chronic inflammation in conducting airways and the alveolar parenchyma. The inflammation, which is a consequence of inhalation of noxious gases like tobacco smoke, has traditionally been thought to be driven by innate immune responses. READ MORE