Search for dissertations about: "copd phenotype"

Showing result 6 - 10 of 13 swedish dissertations containing the words copd phenotype.

  2. 6. T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro

    Author : Pernilla Glader; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Immunologi; serologi; T-cell; inflammation; mucosal immunology; transplantation; serology; Immunology; lymphocyte; chronic obstructive pulmonary disease;

    Abstract : Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. READ MORE

  4. 7. Aspects of inflammation in chronic obstructive pulmonary disease : a clinical study

    Author : Magnus J Löfdahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chronic pbstructive pulmonary disease; bronchoscopy; bronchoalveolar lavage; inflammation; flow cytometry; bronchial biopsies;

    Abstract : Development of chronic obstructive pulmonary disease (COPD) involves an amplified inflammatory response to tobacco smoke that results in a limitation of airflow. At present, the mechanisms underlying these inflammatory processes are not fully understood and insight into these mechanisms could be obtained through comparison of the processes in patients with COPD and appropriate controls. READ MORE

  5. 8. T cells and smoke-induced airway inflammation

    Author : Mikael Mikko; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic obstructive pulmonary disease (COPD) is an inflammatory disease primarily caused by longterm cigarette smoking. The disease is characterized by both tissue remodelling and an accumulation of inflammatory cells including macrophages, neutrophils and T cells, in the lung. READ MORE

  6. 9. Regulation of gene expression in pulmonary inflammation and differentiation : a role for C/EBP transcription factors

    Author : Abraham B Roos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : CCAAT/enhancer-binding protein (C/EBP) transcription factors play essential roles in gene regulation. The lung-enriched isoform C/EBPα is known to inhibit proliferation, promote differentiation and stimulate gene expression characteristic of the mature differentiated pulmonary epithelium. READ MORE

  7. 10. War and peace in the tumor microenvironment : tumor-associated cells as facilitators or adversaries during tumor development

    Author : Margarita Bartish; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The tumor microenvironment, including immune cells, fibroblasts and vasculature, profoundly affects tumor development by initially opposing, but eventually facilitating tumor growth, vascularization and spread. Though corrupted by the growing tumor, such cells remain non-transformed and thus, with proper cues, are possible to direct toward their physiological anti-tumor function. READ MORE