Search for dissertations about: "copper homeostasis"

Showing result 1 - 5 of 7 swedish dissertations containing the words copper homeostasis.

  2. 1. Human copper ion transfer : from metal chaperone to target transporter domain

    Author : Moritz Sebastian Niemiec; Pernilla Wittung-Stafshede; Nigel Robinson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; copper homeostasis; copper chaperone; Atox1; ATP7B; Wilson disease protein; metal transport; size exclusion chromatography; thermodynamics; isothermal calorimetry;

    Abstract : Many processes in living systems occur through transient interactions among proteins. Those interactions are often weak and are driven by small changes in free energy. READ MORE

  4. 2. Structure-function studies of copper flux across cellular membranes

    Author : Niloofar Nayeri; Membranproteinstrukturbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Copper homeostasis; Copper transporter family CTR ; PcoB; CopB;

    Abstract : .... READ MORE

  5. 3. New Approaches for Daphnia magna Toxicity Assessment

    Author : Berkay Paylar; Per-Erik Olsson; Jana Jass; Solomon Asnake; Ajay Pradhan; Joachim Sturve; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Risk assessment; toxicogenomics; zinc; copper; machine learning;

    Abstract : Risk assessment plays a crucial role in evaluating and managing the potential hazards and health effects associated with exposure to substances. In recent decades, the field of risk assessment has undergone significant expansion, embracing innovative approaches and methodologies. READ MORE

  6. 4. Development of a Yeast Model for Functional Analysis of Human Copper Transport Proteins

    Author : Kumaravel Ponnandai Schanmugavel; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; luminal loop; metal binding domains; Wilson’s disease protein; yeast model; ATP7B; copper transport.;

    Abstract : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. It mediates numerous biochemical functions to maintain cellular homeostasis making it an essential metal for sustaining life. READ MORE

  7. 5. Roles of intermolecular interactions in amyloid fibril formation mechanisms

    Author : Tony Werner; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; disulfide-bonds; Atox1; α-synuclein; Aggregation; protein interactions; Parkinson’s disease; β-parvalbumin; macromolecular crowding; osmolytes; Amyloid fibrils;

    Abstract : Amyloid fibrils, a major pathological feature of several neurodegenerative disorders, are highly stable, insoluble aggregates of misfolded proteins. The formation of such aggregates involves a complex equilibrium between protein monomers, different on- and off-pathway transient oligomeric species, and amyloid fibrils. READ MORE