Search for dissertations about: "coreceptor"

Showing result 16 - 20 of 35 swedish dissertations containing the word coreceptor.

  2. 16. Infections with HIV-1 and mycobacterium tuberculosis : the role of HLA class II alleles and HIV phenotypes

    Author : Simani Gaseitsiwe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis (M.tb), are the two infectious diseases causing the greatest number of deaths globally. The burden of these infections is most felt in the developing world particularly in sub-Saharan Africa. This is also a region where some of the studies in this thesis were conducted. READ MORE

  4. 17. HIV-1 variability in relation to host defence mechanisms and disease outcome

    Author : Marianne Jansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV-1; peptides; seroreactivity; genetic variability; pediatric; disease outcome; biological phenotypes; B-chemokines; coreceptors; V3; V2.;

    Abstract : Genetic variability is a major characteristic of HIV-1. Virus variants evolve rapidly, not only globally, but also within single individuals as a result of an error-prone reverse transcriptase, a rapid virus population turnover and selective pressure from the host. READ MORE

  5. 18. Intrahost evolution of HIV-1 phenotypes

    Author : Marie Borggren; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : HIV-1 evolves constantly within an infected individual, due to its mutation-prone viral enzyme, high viral turnover and pressure from the host immune system. Therefore, viruses isolated at different time points from the same individual are never exactly the same and, accordingly, rarely function the same way. READ MORE

  6. 19. A molecular network mediating adventitious root initiation in Arabidopsis thaliana

    Author : Abdellah Lakehal; Catherine Bellini; Malcolm Bennett; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Adventitious rooting; auxin; jasmonate; cytokinin; phytohormone perception and signalling; vegetative propagation;

    Abstract : To adapt to the ever-changing rhizosphere conditions, land plants evolved a sophisticated root system. The genetic determinants of the root system establishment have been the targets of natural selection, resulting in a very complex but robust molecular networks and circuits. READ MORE

  7. 20. Ultra-deep characterization of viral quasispecies in HIV infection

    Author : Charlotte Hedskog; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : HIV-1 has the ability to rapidly diversify and adapt to changes in its environment, such as evading the host immune response, altering cell tropism, and developing resistance to antiretroviral drugs. Minority HIV-1 variants have been shown to be of clinical significance, especially those with non-nucleoside reverse transcriptase inhibitor (NNRTI) drug resistance mutations or determinants of CXCR4 phenotype (X4-virus). READ MORE