Search for dissertations about: "coronary circulation"

Showing result 21 - 25 of 41 swedish dissertations containing the words coronary circulation.

  1. 21. Endothelial dysfunction in patients with glucose abnormalities and coronary artery disease : studies of pathogenesis and treatment

    Author : Magnus Settergren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Type 2 diabetes is associated with endothelial dysfunction, which is characterised by the reduced bioavailability of nitric oxide (NO). This is a result of increased oxidative stress and inflammation and the synthesis of endothelium-dependent vasoconstricting factors such as endothelin-1 (ET-1) caused by hyperglycaemia, insulin resistance and dyslipidemia. READ MORE

  2. 22. Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology

    Author : Yuri Sheikine; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; coronary artery disease; restenosis; chemokines; eicosanoids;

    Abstract : Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel wall. These processes are mediated, among other substances, by molecules belonging to a large family of chemoattractants. READ MORE

  3. 23. The importance of endothelin-1 for vascular function in patients with atherosclerosis and healthy controls

    Author : Felix Böhm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acetylcholine; atherosclerosis; blood flow; circulation; coronary disease; endothelin; endothelium; kidney; liver; nitric oxide; patients; receptors; vasoconstriction.;

    Abstract : Background: Atherosclerosis is associated with endothelial dysfunction, which is an early sign with prognostic implications in patients with coronary artery disease. Atherosclerosis is also associated with enhanced expression of the vasoconstrictor peptide endothelin-1 (ET-1). READ MORE

  4. 24. Augmentation of vital organ blood flow during experimental cardiopulmonary resuscitation

    Author : Rolf Gedeborg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; epinephrine; high-dose epinephrine; buffer; cerebral blood flow; post-resuscitation period; aortic occlusion; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

    Abstract : Clinical outcome from cardiac arrest remains poor. If the time from arrest to restoration of spontaneous circulation can be shortened and resuscitation techniques improved so that higher blood flow and oxygen delivery to vital organs is achieved, it is possible that the outcome from cardiac arrest could improve. READ MORE

  5. 25. Release and Clearance Mechanisms of Cardiac Troponin

    Author : Karin Starnberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; cardiac; Troponin;

    Abstract : Myocardial infarction (MI) is often suspected when a patient presents with chest pain. MI is defined as cardiac necrosis due to ischemia, most often mediated through impaired coronary perfusion. Cardiac necrosis results in the release of myoglobin, creatine kinase and cardiac troponin (cTn) to the circulation. READ MORE