Search for dissertations about: "cortical inhibition"

Showing result 11 - 15 of 73 swedish dissertations containing the words cortical inhibition.

  2. 11. PTEN and Akt signalling in Alzheimer’s disease

    Author : Annika Rickle; Karolinska Institutet; Karolinska Institutet; []
    Keywords : PTEN; Akt; GSK3beta; post-mortem brain; rat primary cortical neurons;

    Abstract : Akt / protein kinase B is an important cell survival kinase that modulates the activity of a range of pro-apoptotic proteins. A major downstream target of Akt is glycogen synthase kinase-3beta (GSK3beta) that phosphorylates the microtubule-associated protein tau. READ MORE

  4. 12. Neural control of standing posture

    Author : Craig Tokuno; Andrew Cresswell; Alf Thorstensson; Marc Carpenter; Thomas Sinkjær; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Medicin Teknik; Medicine Technology; Posture; motor cortex; electromyography; kinematics; H-reflex; pre-synaptic inhibition; transcranial magnetic stimulation;

    Abstract : When humans are asked to stand normally, they are not completely motionless. Rather, small amounts of body movement, termed postural sway, can be observed. Although the postural sway of standing has been well described, the manner in which this sway is neurally controlled and its influence in tasks involving postural re-stabilization are not known. READ MORE

  5. 13. Modulation of AMPA glutamate receptor functions in primary neuronal cultures

    Author : Gvido Cebers; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glutamate; AMPA; cerebellar granule cells; cortical cells; cyclothiazide; AP-1; transcription factors; receptor desensitization; Ca2 ; neurotoxicity; 45Ca2 uptake; apoptosis; ischemia; muscarinic; carbachol;

    Abstract : Primary neuronal cultures were used to investigate the properties of AMPA receptors and functional consequences of their activation, as well as AMPA receptor desensitization and possibilities for its modulation. We established the presence and spontaneous functional activity of AMPA receptors in cerebellar granule and cortical cell cultures. READ MORE

  6. 14. Effects of lipophosphoglycan on macrophage actin dynamics

    Author : Katarina Tejle; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Leishmania donovani is a blood-borne tropicial parasite, which infects humans through bites by Phlebotomine sandflies. The parasite survives and multiplies inside macrophages in inner organs, and causes the deadly disease visceral leishmaniasis (Kala-Azar). Lipophosphoglycan (LPG) is the major surface component of Leishmania donovani promastigotes. READ MORE

  7. 15. Leishmania donovani lipophosphoglycan : effects on actin and phagosomal maturation

    Author : Åsa Holm; Maria Fällman; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Leishmania donovani promastigotes survive intracellularly in macrophages by inhibiting phagosomal maturation. This ability is conferred by surface lipophosphoglycan (LPG), which is transferred to the host-cell plasma and phagosomal membranes during phagocytosis. READ MORE