Search for dissertations about: "cortical microtubule"

Showing result 1 - 5 of 6 swedish dissertations containing the words cortical microtubule.

  2. 1. The Many Facets of bicoid Gradient Formation in Drosophila

    Author : Xiaoli Cai; Stefan Baumgartners grupp Utvecklingsbiologi i invertebrater; []
    Keywords : Drosophila; bicoid; gradient formation; ARTS model; cortical microtubule; drug;

    Abstract : In Drosophila, the Bicoid protein servers as paradigm as the first identified morphogen, whose concentration gradient provides the initial positional information in the anterior half of the embryo. There, it differentially activates segmentation genes, in particular the gap genes. READ MORE

  4. 2. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

    Author : Stefano Pietra; Markus Grebe; Niko Geldner; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Abstract : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. READ MORE

  5. 3. PTEN and Akt signalling in Alzheimer’s disease

    Author : Annika Rickle; Karolinska Institutet; Karolinska Institutet; []
    Keywords : PTEN; Akt; GSK3beta; post-mortem brain; rat primary cortical neurons;

    Abstract : Akt / protein kinase B is an important cell survival kinase that modulates the activity of a range of pro-apoptotic proteins. A major downstream target of Akt is glycogen synthase kinase-3beta (GSK3beta) that phosphorylates the microtubule-associated protein tau. READ MORE

  6. 4. Molecular determinants of endocannabinoid-mediated brain development

    Author : Daniela Calvigioni; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The enchanting process of brain development entails a fragile and finite time window, throughout which biochemical imbalances and external insults can potentially affect developing neuronal circuits. Within the numerous exquisitely orchestrated events taking place in the foetal brain, axonal pathfinding is of paramount importance. READ MORE

  7. 5. Neuronal apoptosis in excitotoxicity : involvement of nitric oxide and cytoskeletal damage

    Author : Emanuela Bonfoco; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the nervous system apoptosis may play an important role in the development of several neurodegenerative diseases. The overall objective of the present work is to investigate at the cellular and molecular levels, the mechanisms by which neurons are signaled to undergo apoptotic cell death after exposure to various effectors, such as nitric oxide (NO) and its byproducts, glutamate, and colchicine. READ MORE