Search for dissertations about: "cost of drug reaction"

Showing result 1 - 5 of 8 swedish dissertations containing the words cost of drug reaction.

  2. 1. Applications of in situ proximity ligation assays for cancer research and diagnostics

    Author : Liza Löf; Masood Kamali-Moghaddam; Ulf Landegren; J.Paul Robinson; Uppsala universitet; []
    Keywords : Cancer; Diagnostics; Research; Prognostics; Method development; Flow cytometry; Drug delivery; Molekylär medicin; Molecular Medicine;

    Abstract : In the field of cancer research and diagnostics it is crucial to have reliable methods for detecting molecules involved in the disease. New and better methods for diagnostics, prognostics and drug delivery therefore remain a permanent aim. READ MORE

  4. 2. Microwave-Assisted Synthesis of C2-Symmetric HIV-1 Protease Inhibitors : Development and Applications of In Situ Carbonylations and other Palladium(0)-Catalyzed Reactions

    Author : Johan Wannberg; Anders Hallberg; David C. Rees; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; HIV; protease inhibitors; palladium; carbonylations; molybdenum hexacarbonyl; dihydropyrimidone; DHPM; microwave; cross-coupling; diazylhydrazines; carbon monoxide; synthesis; C2-symmetric; HIV-1 protease inhibitors; aminocarbonylation; fluorous; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Abstract : The HIV protease is an essential enzyme for HIV replication and constitutes an important target in the treatment of HIV/AIDS. Efficient combination therapies using inhibitors of the reverse transcriptase and protease enzymes have led many to reevaluate HIV infections from a terminal condition to a chronic-but-manageable disease in the developed world. READ MORE

  5. 3. Biosynthesis of capsaicinoids by recombinant Saccharomyces cerevisiae

    Author : Nina Muratovska; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; capsaicinoids; nonivamide; baker’s yeast; Capsicum; Saccharomyces cerevisiae; Pseudomonas putida; lignin-derived substrates; vanillin aminotransaminase; reductive amination; vanillylamine; N-Acyltransferase; CoA-ligase; amide; whole-cell bioconversion; TRPV1 receptor; ion channel; calcium dye Fluo-4; flow cytometry;

    Abstract : Throughout history, people have used products from different microorganisms and plants for many medicinal and nutritional applications. Chilli peppers have been used for spicing up food, but also for their pharmacological properties. READ MORE

  6. 4. Fabrication of Functional Molecularly Imprinted Materials using Nanoparticle Building Blocks

    Author : Changgang Xu; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecularly imprinted polymers; magnetic susceptibility; click chemistry; PFPA; Pickering emulsion; chemical conjugation;

    Abstract : Molecularly imprinted polymers (MIPs) have attracted great interest in many applications including bioseparation, chemical sensing, catalysis, drug delivery, etc. Recently, molecularly imprinted nanoparticles have become accessible due to a number of synthetic methods that have been developed. READ MORE

  7. 5. Molecular Tools for Nucleic Acid Analysis

    Author : Deirdre O'Meara; KTH; []
    Keywords : nucleic acid capture; modular probes; biosensor; bio-magnetic separation; hepatitis C; sequencing; pyrosequencing; mutation detection; HIV-1; drug resistance; SNP; allele-specific extension; apyrase; genotyping.;

    Abstract : Nucleic acid technology has assumed an essential role invarious areas ofin vitrodiagnostics ranging from infectious diseasediagnosis to human genetics. An important requirement of suchmolecular methods is that they achieve high sensitivity andspecificity with a fast turnaround time in a cost-effectivemanner. READ MORE