Search for dissertations about: "costimulatory molecules ISBN 9 1-628-2643-3"

Found 1 swedish dissertation containing the words costimulatory molecules ISBN 9 1-628-2643-3.

2. 1. Triggering and inhibitory molecules affecting target cell recognition by NK cells

   Author : Margarita Salcedo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : NK cell; MHC class 1; NKinhibitory receptors; costimulatory molecules ISBN 9 1-628-2643-3;

   Abstract : NK cells were described originally for their ability to lyse certain tumor cell lines without prior immunization. MHC class I molecules have been shown to deliver a negative signal to NK cells preventing killing of target cells. This reaction is mediated via specific receptors on NK cells, referred to as KIR in man and Ly49 in mouse. READ MORE