Search for dissertations about: "covalent binding"

Showing result 1 - 5 of 87 swedish dissertations containing the words covalent binding.

  2. 1. Development of a covalent site-specific antibody labeling strategy by the use of photoactivable Z domains

    Author : Anna Konrad; Sophia Hober; Hjalmar Brismar; Patrik Samuelsson; KTH; []
    Keywords : antibody labeling; site-specific; covalent; SPPS; Z domain; BPA; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Abstract : The joining of two molecular functions or the strategy of adding functions to proteins has been tremendously important for the development of proteins as tools in research and clinic. Depending on the intended application, there are a wide variety of functions that can be added to a proteins. READ MORE

  4. 2. Complexes of cell-penetrating peptides with oligonucleotides : Structure, binding and translocation in lipid membranes

    Author : Luis Daniel Ferreira Vasconcelos; Ülo Langel; William C. Wimley; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptide; oligonucleotide; transfection; non-covalent complexes; membrane interaction; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : The fundamental element of life known to man is the gene. The information contained in genes regulates all cellular functions, in health and disease. The ability to selectively alter genes or their transcript intermediates with designed molecular tools, as synthetic oligonucleotides, represents a paradigm shift in human medicine. READ MORE

  5. 3. Conformation and dynamics of DNA : effects of covalent binding of benzo(a)pyrene diol epoxide

    Author : Per-Olof Lycksell; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  6. 4. Antibodies and Antibody Mimics in Binding Assays

    Author : Ioana Wärnmark; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polymerteknik; biopolymers; ELISA; antibody; molecularly imprinted polymer; Biochemistry; Biokemi; Metabolism; metabolism; Biokemisk teknik; Polymer technology; Biochemical technology;

    Abstract : This thesis presents development of new analytical methods using antibodies and molecularly imprinted polymers (MIPs) in binding assays: 1) The high specificity of antibodies and the wide variety of efficient labels make immunoassay one of the most popular analytical techniques today. Enzyme-linked immunosorbent assay (ELISA) is most widely used, since the enzyme label can be used as a catalyst to provide very high signal amplification. READ MORE

  7. 5. ALL-OPTICAL CONTROL OF MOLECULAR FUNCTIONS - ENERGY TRANSFER SWITCHING AND INFORMATION PROCESSING

    Author : Magnus Bälter; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; white-light generation; molecular logic; spiropyran; photochromism; DNA-binding; diarylethene; energy transfer; all-photonic; fulgimide; dithienylethene; photoswitch; fluorescence modulation;

    Abstract : In this work, the photoswitching of molecular systems endowed with photochromic functionality have been investigated for the reversible photonic gating of excitation energy transfer (FRET) reactions as well as in application for all-photonic molecular logic. The presented systems involves the integration of photochromic entities within both covalent and non-covalent designs and serves to implicate photonic switching of molecular level phenomena. READ MORE