Search for dissertations about: "covalent immobilization"

Showing result 1 - 5 of 11 swedish dissertations containing the words covalent immobilization.

2. 1. Spatially Controlled Covalent Immobilization of Biomolecules on Silicon Surfaces

   Author : Elisabeth Pavlovic; Sven Oscarsson; Marcus Textor; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; silicon oxide; electrooxidation; sulfur; nanotechnology; self-assembled monolayers; atomic force microscopy; electron spectroscopy for chemical analysis; biomolecules; covalent immobilization; reversibility; Bioteknik; Bioengineering; Bioteknik;

   Abstract : The work described in this thesis aims to achieving surface patterning through chemical activation of thiolated silicon oxide surfaces, resulting in a spatially controlled covalent immobilization of biomolecules with high resolution.Existing chemical methods to immobilize molecules on surfaces do not reach below the micrometer scale while the ones allowing for spatial control mostly lead to non-covalent adsorption of molecules on surfaces, or require several successive chemical reactions to obtain the final covalent immobilization. READ MORE

4. 2. Immobilization and Interaction of Biomolecules at the Solid-Liquid Interface : Applications to Solid-Phase Analytical Techniques

   Author : Ulf Jönsson; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein immobilization; silica; Immunoglobulins; Protein A; Fibronectin; chemical-vapour deposition; silane; ellipsometry; radiolabeling; contact-angle measurement; solid-phase analytical techniques;

   Abstract : The development of solid-phase-analytical techniques based on surface-concentration-measuring devices requires a stable and reproducible immobilization of biomolecules on well-characterized solid surfaces. This study reports on the immobilization of Immunoglobulin G, Protein A and Fibronectin on chemically modified silica surfaces. READ MORE

5. 3. Biosensor surface chemistry for oriented protein immobilization and biochip patterning

   Author : Emma Ericsson; Karin Enander; Sofia Svedhem; Linköpings universitet; []
   Keywords : Biochip; biosensor; hydrogel; ligand; orientation; patterning; photochemistry; protein immobilization; surface chemistry; self-assembled monolayer; SAM;

   Abstract : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. READ MORE

6. 4. Lipase-catalyzed production of structured triacylglycerols

   Author : Ariana Causevic; Bioteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Structured lipids; Lipase; Acyl migration; Immobilization; Lipid analysis; Transesterification; Water activity;

   Abstract : Vegetable oils and fats are major energy sources but also play an essential part in the physical and chemical properties of food products. The current change in the climate is affecting harvest yields, leading to a shortage and increased prices of raw materials that are difficult to replace. READ MORE

7. 5. Bioactive nanocellulose materials for the treatment of chronic wounds

   Author : Anna Blasi Romero; Natalia Ferraz; Daniel Aili; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cellulose nanofibrils; covalent immobilization; wound healing; antioxidant properties; antibacterial properties; anti-inflammatory properties; stimuli responsive hydrogels; reactive oxygen species; host defense peptides; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

   Abstract : Chronic wounds represent a burden for the healthcare system and significantly affect the quality of life of the patients. There is currently a lack of efficient treatments but new, improved therapeutic approaches are under development. READ MORE