Search for dissertations about: "coxibs"
Found 4 swedish dissertations containing the word coxibs.
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1. Pain management in outpatient knee arthroscopy
Abstract : Knee arthroscopy is probably the most common orthopaedic procedure performed. The objective of this thesis was to compare local anaesthesia with other used anaesthetic techniques for outpatient knee arthroscopy. READ MORE
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2. Venous thromboembolism in women : an assessment of hormonal, genetic and other risk factors
Abstract : Background: Venous thromboembolism (VTE) occurs in 1-2 in 1000 individuals per year. VTE is found in both sexes, but women have a higher incidence at younger ages, particularly during the childbearing years. READ MORE
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3. Characterization of the PGE2 pathway in arthritis and inflammation : mPGES-1 as a therapeutic target
Abstract : The inducible prostaglandin (PG) E2 pathway is defined by the concerted activities of the enzymes cyclooxygenase (COX)-2 and microsomal prostaglandin E synthase (mPGES)-1 in producing PGE2. PGE2 has pro-inflammatory and immunomodulatory functions and is involved in an array of diseases with an autoimmune and chronic inflammatory component, including rheumatoid arthritis (RA). READ MORE
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4. Structure and function of microsomal prostaglandin E synthase-1
Abstract : The glutathione-dependent enzyme microsomal prostaglandin E synthase-1 (MPGES1) plays a pivotal role in inflammatory diseases. MPGES1 is up-regulated by pro-inflammatory cytokines in concert with cyclooxygenase (COX) -2, and the concerted action of both enzymes leads to the production of induced prostaglandin E2 (PGE2), a potent lipid mediator of inflammation, pain, and fever. READ MORE