Search for dissertations about: "cross-protection"

Showing result 1 - 5 of 7 swedish dissertations containing the word cross-protection.

  2. 1. Streptococcal protein Rib and related proteins: a family of repetitive surface proteins that elicit protective immunity

    Author : Margaretha Stålhammar-Carlemalm; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; cross-protection; epithelial cell adhesion; protective immunity; vaccination; surface proteins; Group B streptococcus; Streptococcus pyogenes; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : ABSTRACT Streptococci constitute a heterogeneous group of Gram-positive bacteria, divided into different serological groups on the basis of antigenic differences in a cell wall-associated carbohydrate. This thesis describes related surface proteins expressed by bacteria in two of these groups, the group B streptococcus (GBS) and the group A streptococcus (GAS). READ MORE

  4. 2. Puumala hantavirus : immune responses and vaccines

    Author : Cristina de Carvalho Nicacio; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hantavirus; Puumala virus; nucleocapsid protein; neutralizing antibodies; Fab fragment; combinatorial library; phage-display; IgA; cellular immunity; cross-protection; intranasal vaccination;

    Abstract : Hantaviruses (family Bunyaviridae) is a group of closely related zoonotic rodent-borne viruses that are transmitted to humans through inhalation of infected rodent excreta. They cause hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS) with varying degree of severity depending on the causative virus. READ MORE

  5. 3. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model

    Author : Åsa Melhus; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; conjugate vaccine; protection; virulence; acute otitis media; Haemophilus influenzae; animal model; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. READ MORE

  6. 4. Oxidative stress on mammalian cell cultures during recombinant protein expression

    Author : Tomás McKenna; Carl-Fredrik Mandenius; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : When the cell is under stress arising from oxidation, heat, infection, toxic contamination or any other stressful condition, proteins may unfold and expose residues in their structure that under normal physiological conditions are hidden and shielded from chemical reactions.In this licentiate thesis the effects of general oxidative stress on the production of recombinant protein by mammalian cells are considered. READ MORE

  7. 5. Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host

    Author : Sigrun Thorsdottir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Streptococcus pneumoniae is a highly relevant pathogenic bacterium, responsible for a large fraction of deaths and disease morbidity in the world. The pneumococcus remains the leading cause of life-threatening pneumonia, septicemia and meningitis beyond neonatal age, despite global implementation of vaccination programs. READ MORE