Search for dissertations about: "cross-reactivity"

Showing result 1 - 5 of 75 swedish dissertations containing the word cross-reactivity.

  2. 1. Molecular basis for enhanced T-cell recognition and cross-reactivity

    Author : Eva Allerbring; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : T cells of the adaptive immune system recognize and kill infected cells by interacting with pathogenic peptides displayed on major histocompatibility complexes (MHC) through its T-cell receptor (TCR). TCR interactions with peptide/MHC complexes occur throughout the lifespan of T cells, from development to activation, with the origin of the peptide varying between self and foreign. READ MORE

  4. 2. Experimental and Clinical Studies on Contact Allergy to Diphenylmethane-4,4′-diisocyanate and Related Substances

    Author : Haneen Hamada; Yrkes- och miljödermatologi; []
    Keywords : 4; 4′-MDI; freund s complete adjuvant; Guinea pig maximization test; 4; 4 -MDA; 4; 4 -DMDA; 4; 4 -DMDI; PPD; p-phenylenediamine; 2; 4-TDI; Toluene diisocyanate; trimer; FCA; Cross-reactivity; dermal uptake; contact allergy; contact dermatitis;

    Abstract : The exposure to isocyanates is more of an occupational problem than a consumer problem. The main route of exposure is assumed to be through inhalation. Isocyanates that have high vapor pressure, such as TDI, can be airborne at room temperature. Other isocyanates such as MDI are volatile only when heated. READ MORE

  5. 3. Novel Bioinformatics Applications for Protein Allergology, Genome-Wide Association and Retrovirology Studies

    Author : Álvaro Martínez Barrio; Erik Bongcam-Rudloff; Teresa K Attwood; Uppsala universitet; []
    Keywords : data integration; web services; protein allergology; risk assessment; cross reactivity; endogenous retroviruses; ERV; dog; canine; GWAS; genome-wide association studies;

    Abstract : Recently, the pace of growth in the amount of data sources within Life Sciences has increased exponentially until pose a difficult problem to efficiently manage their integration. The data avalanche we are experiencing may be significant for a turning point in science, with a change of orientation from proprietary to publicly available data and a concomitant acceptance of studies based on the latter. READ MORE

  6. 4. GH Secretion in children. Methodological aspects of determining immunoreactive and bioactive isoforms

    Author : Chatarina Löfqvist; Göteborgs universitet; []
    Keywords : Growth hormone; immunoassay; cross-reactivity; standard; antibody; insulin-like growth factor 1; reference values;

    Abstract : A child's hormone-dependent growth is dependent on multiple factors, although linear growth is closely associated with levels of growth hormone (GH) secretion. As GH in serum exists in several isoforms, some of which may not be identified by immunoassay, possible alterations in the secretion of these different isoforms in childhood may influence growth and/or metabolism. READ MORE

  7. 5. Characterization of antibody specificity using peptide array technologies

    Author : Björn Forsström; Mathias Uhlén; Markus Templin; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibody; Epitope mapping; Peptide array; Suspension bead array; Antigen; Specificity; Cross-reactivity; Immunization; Immunogenicity; Bioteknologi; Biotechnology;

    Abstract : Antibodies play an important role in the natural immune response to invading pathogens. The strong and specific binding to their antigens also make them indispensable tools for research, diagnostics and therapy. READ MORE