Search for dissertations about: "crossover rate"

Showing result 1 - 5 of 24 swedish dissertations containing the words crossover rate.

  2. 1. Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications

    Author : Lars Ängquist; Matematisk statistik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; programming; actuarial mathematics; Statistik; cytogenetics; Genetik; cytogenetik; Mathematics; Matematik; Statistics; operations research; Genetics; ROC curves; conditioning loci; optimal score functions; noncentrality parameter; cost adjusted relative efficiency; exponential tilting; importance sampling; Monte Carlo simulation; normal approximation; crossover rate; process maximum; analytical approximation; significance calculations; NPL score; conditional linkage analysis; two-locus linkage analysis; Allele sharing; aktuariematematik; operationsanalys; programmering; gene-gene interaction; composite hypotheses; genetic disease models; classes of score functions; nonparametric linkage analysis;

    Abstract : In linkage analysis or, in a wider sense, gene mapping one searches for disease loci along a genome. This is done by observing so called marker genotypes (alleles) and phenotypes (affecteds/unaffecteds) of a pedigree set, i.e. READ MORE

  4. 2. Morbidity in Ménières disease : aspects on quality of life and triggering factors

    Author : Anne-Charlotte Hessén Söderman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Menieres disease; ELS; gentamicin; vestibular neurectomy; outcome assessment; health related-quality of life; sense of coherence; stress; case-crossover.;

    Abstract : Menieres disease is an inner ear disorder of unclear origin, characterized by severe attacks of simultaneously appearing fluctuant hearing loss, vertigo, tinnitus and a feeling of aural fullness. The disease has a well-known natural course. READ MORE

  5. 3. Prehospital advanced airway management in the Nordic countries

    Author : Mikael Gellerfors; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tracheal intubation (TI) is often the preferred technique to secure the airway of an unconscious patient in the prehospital setting. Prehospital TI is associated with several challenges, including limited assistance, few airway rescue devices and environmental difficulties. READ MORE

  6. 4. Structure Evolution during Phase Separation and Gelation of Biopolymer Mixtures

    Author : Niklas Lorén; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; microstructure; gelatin maltodextrin; biopolymer mixtures; structure evolution; phase separation; stereology; confocal laser scanning microscopy; image analysis; spinodal decomposition; transmission electron microscopy; gelation;

    Abstract : This thesis focuses on the kinetics of phase separation and gelation in aqueous mixtures of gelatin and maltodextrin. The structure evolution of these mixtures at different length scales was recorded by confocal laser scanning microscopy (CLSM) and transmission electron microscopy (TEM). The microstructure was quantified by image analysis. READ MORE

  7. 5. Volume effects of albumin infusion in humans

    Author : Markus Zdolsek; Folke Sjöberg; Robert Hahn; Simon Farnebo; Peter Bentzer; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: The use of colloids when treating a patient for hypovolemia has been debated throughout the years. During the last decade, albumin solutions have become the colloids of choice in both operating theatres and intensive care settings when crystalloid fluids are insufficient. READ MORE