Search for dissertations about: "cryo-EM"

Showing result 1 - 5 of 34 swedish dissertations containing the word cryo-EM.

  2. 1. Cryo-EM Studies of Macromolecular Complexes from Photosynthetic Organisms

    Author : Annemarie Perez Boerema; Alexey Amunts; Mei Li; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; cryo-EM; membrane proteins; photosynthesis; translation; chloroplast; ribosome; photosystem I; protein structure; Biochemistry; biokemi;

    Abstract : Plants, algae, and cyanobacteria convert light energy into chemical energy through the process of photosynthesis, fueling the planet and making life as we know it possible. Photosystem I (PSI) is one of the main photosynthetic complexes, responsible for this process. READ MORE

  4. 2. Structural characterisation of mitochondrial macromolecular complexes using cryo-EM : Mitoribosome biogenesis and respiratory chain supercomplex

    Author : Sorbhi Rathore; Martin Ott; Daniel Wilson; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitoribosome biogenesis; mitoribosome assembly factors; yeast respiratory supercomplexes; single particle electron cryo-microscopy; cryo-EM sample preparation; Biochemistry; biokemi;

    Abstract : Mitochondria, popularly known as powerhouse of the cell, contain specialised mitoribosomes that synthesise essential membrane proteins. These essential proteins are required to form enzyme complexes, which carry out the process of oxidative phosphorylation (OXPHOS). READ MORE

  5. 3. Cryo-EM and Computational Biology of Macromolecular Complexes

    Author : Andrew Emmerich; Suparna Sanyal; Erik Lindahl; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The ribosome is a large, ancient multicomponent macromolecular complex which is highly amenable to study by cryogenic electron microscopy (cryo-EM) and computation biology methods. This thesis delves into the structure of both prokaryotic and eukaryotic ribosomes in the context of determining a solution to emerging antimicrobial resistance. READ MORE

  6. 4. Fast and reliable alignment and classification of biological macromolecules in electron microscopy images

    Author : Björn Forsberg; Erik Lindahl; Sriram Subramaniam; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; cryo-EM; electron microscopy; GPU; parallel processing; protein structure; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : In the last century, immense progress has been made to charter and understand a wide range of biological phenomena. The origin of genetic inheritance was determined, showing that DNA holds genes that determine the architecture of proteins, utilized by the cell for most functions. READ MORE

  7. 5. Elucidating the molecular basis of Na+/H+ exchange

    Author : Pascal F. Meier; David Drew; Simon Newstead; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary-active transporter; Solute Carrier Transporter; ion-exchange; sodium proton exchanger; potassium proton exchanger; protein structure; cryo-EM; regulation; biokemi; Biochemistry;

    Abstract : Solute carrier (SLC) transporters are membrane transport proteins, which catalyse the movement of nutrients, ions, and drugs across cell membranes. Here, I will present our contribution to understanding the mechanism of the sodium/proton exchangers (NHE), belonging to the SLC9 family of membrane transporters. READ MORE