Search for dissertations about: "cultured human fibroblasts."

Showing result 1 - 5 of 38 swedish dissertations containing the words cultured human fibroblasts..

  2. 1. Differentiation of Human Dermal Fibroblasts : a New Tool in Vascular Tissue Engineering

    Author : Lisa Karlsson; Gunnar Kratz; Magnus Grenegård; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Tissue engineering is an expanding field, which focuses on the development of func-tional substitutes for damaged tissues. A limitation in this field is difficulties with obtaining autologous cells. Recent research has shown the presence of cells with multilineage-potential within the connective stroma of the skin. READ MORE

  4. 2. Responses of fibroblasts and chondrosarcoma cells to mechanical and chemical stimuli

    Author : Juha Piltti; Mikko Lammi; Jukka Häyrinen; Frank Beier; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rho-kinase inhibition; Y-27632; hypoxia; cyclic stretching; human chondrosarcoma 2 8 cells; chondrocyte phenotype; fibroblasts; proteomics; protein pathway analytics; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Osteoarthritis is an inflammation-related disease that progressively destroys joint cartilage. This disease causes pain and stiffness of the joints, and at advanced stages, limitations to the movement or bending of injured joints. Therefore, it often restricts daily activities and the ability to work. READ MORE

  5. 3. Biochemical and molecular studies of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency in cultured human fibroblasts

    Author : Nikolaos Venizelos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency; trifunctional protein; cultured human fibroblasts.;

    Abstract : Inborn defects in mitochondrial B-oxidation of fatty acids are a group of diseases affecting humans usually early in life. At least 15 separate defects affecting the mitochondrial fatty acid B-oxidation in man have been identified . READ MORE

  6. 4. Models of alveolar remodeling in chronic lung disease

    Author : Oskar Rosmark; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Extracellular matrix ECM ; Decellularization; Mass Spectrometry MS ; Biomechanics; Chronic obstructive pulmonary disease COPD ; Idiopathic pulmonary fibrosis IPF ; Alveolar epithelial cells; Fibroblasts; Lung slices;

    Abstract : Lung function is highly dependent on the structure of the lung parenchyma. Remodeling of the alveolar compartment is a central part of the pathology of chronic lung disease such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). READ MORE

  7. 5. Functional Characterization of Tyrosine Transporters in fibroblast from Healthy Controls and Schizophrenic Patients

    Author : Ravi Vumma; Nikolaos Venizelos; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblasts; Schizophrenia; Precursor of Dopamine; Biological Transport; Active cellphysiology; Tyrosine and alanine transport; System-L; LAT1; LAT2; LAT3; LAT4; MEDICINE; MEDICIN; Internal medicine; Invärtesmedicin; Neurology; Neurologi; Neurology; Neurologi;

    Abstract : Cultured human fibroblasts offer an advantageous system to investigate the amino acid transport properties without confounding the affects of disease state and its treatment in many systemic psychiatric disorders. In previous studies, fibroblast cells have been used to investigate the tyrosine transport across plasma membranes in patients with schizophrenia and autism with out characterizing the particular amino acid transporters. READ MORE