Search for dissertations about: "cultured tumor cells"
Showing result 1 - 5 of 110 swedish dissertations containing the words cultured tumor cells.
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1. Tumor cell heterogeneity profiling using single-cell analysis
Abstract : Cancer is a diverse disease with large variations between tumor types and patients regarding tumor progression and prognosis. Additionally, most individual tumors are heterogeneous, containing subpopulations of cells with various characteristics. READ MORE
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2. Allogeneic dendritic cells as adjuvants in cancer immunotherapy
Abstract : In recent years, immunotherapeutic approaches have achieved remarkable successes through checkpoint blockade antibodies, advances in the use of chimeric antigen receptor (CAR) T cells and new insights into the immunosuppressive role of the tumor microenvironment (TME). Through the advances, the role of cancer vaccines based on ex vivo manipulated autologous dendritic cells (DC) has been challenged. READ MORE
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3. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation
Abstract : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. READ MORE
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4. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer
Abstract : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. READ MORE
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5. Hypoxia and Stem Cells in Normal and Tumor Development
Abstract : Neuroblastoma is a childhood malignancy of the sympathetic nervous system and accounts for 15% of all cancer-related deaths in children. To understand the biology behind neuroblastoma, clarify timing of cellular events and expression profiles of proteins preceding neuroblastoma initiation, we need more relevant preclinical models. READ MORE