Search for dissertations about: "curli"
Showing result 1 - 5 of 18 swedish dissertations containing the word curli.
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1. Contact activation on bacterial surfaces - a virulence mechanism
Abstract : Life-threatening conditions from bacterial infections are a major clinical problem. During a severe infection, the host responds by a massive release of pro-inflammatory mediators together with a systemic activation of systems such as the coagulation, fibrinolytic, and complement systems. READ MORE
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2. Synthesis of substituted Ring-Fused 2-Pyridones and applications in chemical biology
Abstract : Antibiotics have been extensively used to treat bacterial infections since Alexander Fleming’s discovery of penicillin 1928. Disease causing microbes that have become resistant to antibiotic drug therapy are an increasing public health problem. READ MORE
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3. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE
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4. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs
Abstract : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. READ MORE
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5. Nucleator-driven assembly of curli organelles and their pathophysiological role in E. coli septic shock
Abstract : The understanding of how polymeric surface structures are assembled in bacteria is one of general interests, which can provide insight into details of macromolecule interactions, and study how proteins fold into domains as assembly modules for building organelles. Protein-protein interactions in various subcellular compartments lead to the assembly of fimbriae at bacterial cell surfaces. READ MORE