Search for dissertations about: "cutaneous absorption"

Found 4 swedish dissertations containing the words cutaneous absorption.

  2. 1. Cutaneous microdialysis : a technique for human in vivo sampling

    Author : Thomas Andersson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Microdialysis enables in vivo sampling of endogenous and exogenous substances in the interstitial fluid. A probe equipped with a tubular semi-permeable dialysis membrane is inserted into the skin, and perfused with a physiological solution. READ MORE

  4. 2. New insights in contact allergy and drug delivery. A study of formulation effects and hapten targets in skin using two-photon fluorescence microscopy

    Author : Carl Simonsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; contact allergy; cubic phases; cutaneous absorption; bromobimane; isothiocyanate; lipid vesicles; nano; pilosebaceous unit; ; two-photon microscopy;

    Abstract : The skin is a remarkable barrier, protecting us from invasion of e.g. harmful microorganisms and UV-radiation. However, the skin is not adopted to resist repeated exposure to the multitude of xenobiotics introduced into modern society. READ MORE

  5. 3. Clinical and experimental studies on HFE and other genes involved in iron homeostasis

    Author : Petra Holmström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hereditary hemochromatosis; iron overload; HFE gene mutations; porphyria cutanea tarda; HFE gene; iron metabolism-related genes; iron homeostasis; liver; inflammation; and hepatocellular carcinoma;

    Abstract : In this thesis, the clinical significance of HFE mutations was further investigated, and the molecular mechanisms underlying the disturbed iron homeostasis during hemochromatosis, inflammation and hepatocellular carcinoma were studied in experimental models. Hereditary hemochromatosis (HH) is a prevalent autosomal recessive iron overload disorder caused by increased intestinal absorption and deposition of iron in vital organs, leading to organ damage. READ MORE

  6. 4. Plasminogen in periodontitis and wound repair

    Author : Rima Sulniute; Tor Ny; Daniel A Lawrence; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The plasminogen activator (PA) system plays a critical role in many physiological and pathological processes, such as fibrinolysis, extracellular matrix (ECM) degradation, wound healing, inflammation, and cancer. The key component of the PA system is plasmin, a broad-spectrum serine protease that is derived from its inactive form, plasminogen. READ MORE