Search for dissertations about: "cyclin B1"

Showing result 1 - 5 of 16 swedish dissertations containing the words cyclin B1.

  1. 1. The Prognostic Impact of Proliferation Markers in Breast Cancer with Emphasis on Cyclin B1 and PPH3

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anthoula Koliadi; Uppsala universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proliferation; cyclin B1; Phosphorylated Histone 3; cyclin A; breast cancer; node negative; prognostic factor; luminal; Oncology; Onkologi;

    Abstract : The aim of this thesis was to investigate the prognostic role of the proliferation markers cyclin B1 and Phosphorylated Histone 3 (PPH3) in breast cancer (BC).In paper I we used an experimental study design, we compared women dying early from their BC with women free from relapse more than eight years after initial diagnosis. READ MORE

  2. 2. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

    University dissertation from Oncology, Lund

    Author : Marie Klintman; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

    Abstract : Popular Abstract in Swedish Varje år insjuknar mer än 8000 kvinnor i Sverige i bröstcancer, och 5 år efter diagnos är nära 90% fortfarande i livet. Trots att prognosen för majoriteten av patienterna är god, dör 1400 kvinnor årligen av bröstcancer. READ MORE

  3. 3. Prognostic and treatment predictive factors for radio- and chemotherapy resistance in breast cancer patients- a step towards personlized medicine

    University dissertation from Emma Niméus-Malmström, Dept of Oncology

    Author : Emma Niméus; Lunds universitet.; Lund University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 2-DE; cyclin B1; breast cancer; radioresistance; immunohistochemistry; chemotherapy resistance; gene expression; treatment prediction; prognosis;

    Abstract : Breast cancer is the most common cancer form among women in the Western world. Although treatment has improved during the last decades, there is still a significant proportion of the patients who are not cured. READ MORE

  4. 4. Cyclins on the move : a time and a place for cyclin A2 and cyclin B1 in the human cell cycle

    University dissertation from Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Author : Helena Silva Cascales; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The ultimate aim of the cell cycle is to create an identical daughter cell. Therefore, correct progression through the different phases of the cell cycle is crucial to ensure faithful cell division. READ MORE

  5. 5. Regulation of CDK dephosphorylation in mitotic entry

    University dissertation from Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Author : Arne Lindqvist; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cell cycle progression is orchestrated by the activity of a Cyclin dependent kinase (Cdk) in complex with a Cyclin. The key regulator of early mitotic events is the Cyclin B1/Cdk1 complex. In G2, Cyclin B1/Cdk1 is kept inactive by phosphorylation in the active site of Cdk1. READ MORE