Search for dissertations about: "cyclization"

Showing result 1 - 5 of 40 swedish dissertations containing the word cyclization.

  1. 1. Palladium(II)-Catalyzed Oxidative Cyclization Strategies Selective Formation of New C-C and C-N Bonds

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Andreas K. Å. Persson; Stockholms universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbocyclization; Palladium Catalysis; Oxidation; Cyclization; Enallenes; Aza-Enallenes; Dienallenes; Allenylation; Oxazolidinones; Biomimetic; Arylation; Borylation; Transmetallation; Organic Chemistry; organisk kemi;

    Abstract : The main focus of this thesis has been directed towards preparation and oxidative carbocyclization of en-, dien- and aza-enallenes.In the first part of this thesis, a stereoselective oxidative carbocyclization of dienallenes was realized. READ MORE

  2. 2. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Stefan Berlin; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; radical; cyclization; carbonylation; melatonin; pyrrolidine; pyrrolidin-3-one; tetrahydrofuran-3-one; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. READ MORE

  3. 3. Radical Cyclization Approaches to Pyrrolidines

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Beşev; Uppsala universitet.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Radical cyclization; diastereselectivity; pyrrolidine; pyrroline; thiazoline; aziridine; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. READ MORE

  4. 4. Synthesis of Aldehyde-Functionalized Building Blocks and Their Use for the Cyclization of Peptides Applications to Angiotensin II

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Petra Johannesson; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Synthesis; Aldehyde; Cyclization; Peptide; Angiotensin II; Ang II; Bioactive Conformation; Solid Phase Peptide Synthesis; Dimethyl Acetal; Farmaceutisk kemi; Syntes; Aldehyd; Cyklisering; Peptid; Bioaktiv konformation; Fast-fas peptidsyntes; Dimetylacetal; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Abstract : This study addresses the issue of how to convert peptides into drug-like non- peptides with retained biological activities at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. READ MORE

  5. 5. Pyrrolidines via Radical Cyclization

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Besev; Uppsala universitet.; [2000]
    Keywords : ;

    Abstract : .... READ MORE