Search for dissertations about: "cyclization"
Showing result 6 - 10 of 41 swedish dissertations containing the word cyclization.
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6. Transition-Metal Catalyzed Synthesis of Small- and Medium-Sized Rings Applications toward oxazole synthesis, cycloheptadienes, and natural products
Abstract : This thesis deals with the development of novel methodologies for the synthesis of hetero- and carbocycles enabled by transition metal catalysis. The second chapter of the thesis describes a gold-catalyzed three-component reaction to form a variety of substituted oxazoles from readily available N-benzylimines, terminal alkynes, and acyl chlorides. READ MORE
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7. Metal‐Free Arylations of Oxygen and Nitrogen Nucleophiles : Applications of Diaryliodonium Salts
Abstract : This thesis concerns development of new methods for metal‐free arylations in organic synthesis. The protocols discussed in the thesis are based on a class of hypervalent iodine compounds called diaryliodonium salts. These reagents are known to transfer aryl moieties to suitable nucleophiles. READ MORE
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8. Construction of Five-Membered Heterocycles via Radical Cyclization
Abstract : .... READ MORE
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9. Development of Peptide Binders : Applied to Human CRP, Carbonic Anhydrase (II, IX) and Lysine Demethylase 1
Abstract : In this thesis, a polypeptide binder concept is illustrated. By conjugation to a set of sixteen polypeptides, a small binding molecule can evolve into a polypeptide binder with increased affinity and selectivity. READ MORE
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10. Carbon-Carbon Bond Formation via Radical Cyclization and Transition Metal Catalysis
Abstract : Free radical cyclization methodology has been used extensively in synthesis for manipulation of complex molecules such as alkaloids, terpenes, carbohydrates, peptides and nucleic acids. The methodology has emerged as a result of work by physical organic chemists who determined rate constants for the most common radical reactions used in organic synthesis. READ MORE