Search for dissertations about: "cysteinyl-leukotrienes"

Showing result 1 - 5 of 35 swedish dissertations containing the word cysteinyl-leukotrienes.

  2. 1. Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle

    Author : Eva Wikström Jonsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : cysteinyl leukotrienes; leukotriene receptor; histamine; antigen; smooth muscle; lipoxin; thromboxane; Schultz-Dale reaction;

    Abstract : The cysteinyl leukotrienes (leukotriene C4, D4 and E4) have potent biological actions which significantly contribute to the airway obstruction in asthma. Several of these effects are blocked by drugs known as CysLT1-receptor antagonists, which have been introduced as new treatment for asthma. READ MORE

  4. 2. Studies of receptors and modulatory mechanisms in functional responses to cysteinyl-leukotrienes in smooth muscle

    Author : Magnus Bäck; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cysteinyl-leukotrienes, i.e. leukotriene (LT) C4, D4 and E4, are inflammatory mediators and potent airway- and vasoconstrictors. Two different cysteinyl-leukotriene receptors have been cloned, CysLT, and CysLT2. READ MORE

  5. 3. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide

    Author : Gerd Lärfars; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Polymorphonuclear granulocytes; inflammation; nitric oxide; leukotrienes; tumor necrois factor; rheumatoid arthritis; interferon-gamma; chronic granulomatous disease;

    Abstract : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. READ MORE

  6. 4. Studies on the regulation and function of lipoxygenases in Hodgkin lymphoma

    Author : Hongya Han; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hodgkin lymphoma (HL) is a unique entity among the lymphomas, with a minority of malignant Hodgkin and Reed-Sternberg (H-RS) cells surrounded by a broad range of infiltrating cells. The infiltration of certain inflammatory cells has been reported to predict prognosis of the disease. READ MORE

  7. 5. Signalling and trafficking of the cysteinyl leukotriene receptors in intestinal epithelial cells

    Author : Ladan Parhamifar; Malmö Cellpatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trafficking; Cysteinyl leukotriene receptors; inflammation; cytosolic phospholipase A2; colon cancer;

    Abstract : Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. READ MORE