Search for dissertations about: "cysteinyl-leukotrienes"

Showing result 11 - 15 of 35 swedish dissertations containing the word cysteinyl-leukotrienes.

  2. 11. Leukotriene D4-induced signal transduction in human epithelial cells

    Author : Eva Grönroos; Else Kay Hoffmann; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Although the structures of the cysteinyl-leukotrienes have been known for almost twenty years, and their biological effects for almost sixty years, very little is known about the signaling propenies of these compounds. The aim of the present research was to further elucidate the components that are involved in the signaling mechanisms of leukotriene D4 (L TD4) in a human epithelial cell line. READ MORE

  4. 12. Non-invasive analysis of leukotrienes as biomarkers of airway inflammation : method development and clinical applications

    Author : Flora Gaber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Airway inflammation; aspirin-intolerant asthma; biomarker; exhaled breath condensate; FENO; induced sputum; leukotrienes; 5-lipoxygenase; non-invasive analysis; saliva;

    Abstract : Asthma and chronic obstructive pulmonary disease (COPD) are two common diseases characterized by chronic airway inflammation, but the inflammation in asthma is different from the one in COPD. In addition, asthma is a heterogeneous disease presenting with many different phenotypes (e.g. READ MORE

  5. 13. Analysis of epithelial electrophysiological function in paediatric intestinal biopsies

    Author : Annika Reims; Göteborgs universitet; []
    Keywords : Cystic fibrosis; CFTR; coeliac disease; Ussing chamber; intestinal permeability; ion transport; leukotriene; human; duodenum;

    Abstract : Intestinal biopsies are routinely taken from children under investigation of failure to thrive, diarrhoea, abdominal pain and/or malnutrition. These biopsies are usually only evaluated morphologically, i.e. no information is collected with regard to mucosal function. READ MORE

  6. 14. The role of CysLT1R in animal models of colorectal cancer

    Author : Sayeh Savari; Malmö Cellpatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cysteinyl leukotrienes (LTC4, LTD4 and LTE4) are potent pro-inflammatory lipids derived from arachidonic acid and mediate their effect through CysLT1R and CysLT2R. There is a strong correlation between long-standing inflammatory bowel disease where these pro-inflammatory mediators are abundant and colorectal cancer. READ MORE

  7. 15. Studies on cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in lymphomas

    Author : Frida Schain; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Classical Hodgkin lymphoma (cHL) is a malignant disorder with striking inflammatory features. Since cysteinyl leukotrienes (cysLTs) are potent inflammatory mediators it was of interest to study their potential role in the pathogenesis of cHL. READ MORE