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Showing result 1 - 5 of 26 swedish dissertations matching the above criteria.

  2. 1. Molecular mechanisms and immunomodulatory approaches in acute cystitis

    Author : Daniel Butler; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; acute cystitis; Immunomodulation; IL-1beta; hyper inflammatory disorder; neurokinins;

    Abstract : hand in the fight against resistant microbes. This thesis discusses the feasibility and potential of specific immunotherapy in treating acute bacterial infections and chronic sequels. The infection model is acute cystitis; the most common form of urinary tract infection, affecting millions of patients annually. READ MORE

  4. 2. Serum Amyloid A Protein (SAA) in Healthy and Infected Individuals

    Author : Anders Lannergård; Göran Friman; Anders Larsson; Uwe Ewald; Jonas Hedlund; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; acute phase proteins; adult; Administration Oral; aminoglycosides; amyloidosis; antibiotics; bacterial infections; body temperature; C-reactive protein; cefuroxime; cystitis; cytokines; elderly; infant; interleukin-6; newborn; pyelonephritis; serum amyloid A protein; virus diseases; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Abstract : Serum amyloid A protein (SAA) is an acute phase protein that has recently gained increasing interest as a potential marker for disease and treatment monitoring. We investigated SAA and CRP levels in (a) patients with various common infectious diseases (n=98), (b) patients with pyelonephritis (n=37) versus patients with cystitis (n=32), (c) healthy individuals of varying ages (n=231), (d) very immature newborn infants with or without nosocomial infections (NIs) (n=72) and (e) patients with bacterial infections treated with cefuroxime (n=81). READ MORE

  5. 3. Functional studies of purinergic and cholinergic interactions in the rat urinary bladder - Characterization of ATP-evoked urothelial release of acetylcholine

    Author : Johanna Stenqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; acetylcholine; urothelium; caveolae; afferents; cystitis;

    Abstract : Functional interplays between different transmitter systems are known to affect the signalling of the micturition reflex arc. The functional implications of many of these interactions, such as between ATP and acetylcholine, have yet to be unravelled. READ MORE

  6. 4. On the autonomic control of the lower urinary tract. Functional and morphological aspects in the normal and the inflamed urinary bladder

    Author : Daniel Giglio; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscarinic receptor; purinoceptor; adrenoceptor; nitric oxide; in vitro; in vivo; cystometry; Western blot; immunohistochemistry; cystitis; cyclophosphamide; urinary bladder; rat;

    Abstract : The regulation of urinary bladder function involves interplay of signalling systems. Disturbances in any of the interactive systems may result in lower tract dysfunction, which is often apparent to the patient by urge to void or by incontinence, irrespectively of the cause to the lower tract syndrome. READ MORE

  7. 5. Molecular determinants of disease severity in urinary tract infection

    Author : Ines Ambite; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Asymptomatic bacteriuria; urinary tract infection; acute pyelonephritis; cystitis; Escherichia coli 83972; host response; NlpD; RNA Polymerase II; transcription regulation; inflammasome; Il-1β; ASC; NLRP-3; hyper-inflammatory disorder; MMP-7; IL-1RA; genetic susceptibility; IRF-7; siRNA therapy; P fimbriae; type 1 fimbriae;

    Abstract : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. READ MORE