Search for dissertations about: "cytisine"

Found 3 swedish dissertations containing the word cytisine.

  2. 1. Synthesis and Applications of P-chirogenic Phosphine Boranes

    Author : Magnus Johansson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytisine; gold I catalysis lipase; P-chirogenic; desymmetrization; phosphine; enantioselective cyclopropanation. enantioselective deprotonation; chirality; asymmetric synthesis; borane;

    Abstract : AbstractThis thesis reports the independent synthesis of both enantiomers of P-chirogenic phosphine ligands and the building blocks thereof, which are suitable for parallel synthesis efforts and for the generation of more diverse libraries of P-chirogenic compound. The use of P-chirogenic phosphine boranes in transition metal-catalyzed reactions, such as palladium-catalyzed allylic alkylation and amination, is also described. READ MORE

  4. 2. Cholinergic receptors in human prenetal brain : presence, distribution and influence of nicotine and ethanol

    Author : Lena Falk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Events early in life, including exposure to various compounds, may cause disturbances in brain development. Both maternal smoking and alcohol drinking during pregnancy can induce preand postnatal death, cognitive and neurobehavioral disturbances. READ MORE

  5. 3. Development of nicotinic receptor ligands for positron emission tomography - from in vitro to in vivo : Binding studies of neuronal nicotinic acetylcholine receptors using different ³H-, ¹1C- and `6Br - labeled ligands

    Author : Wiebke Sihver; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; nicotinic acetylcholine receptor; PET-ligand; in vitro; in vivo; Alzheimer s disease; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in central processes, such as cognitive functionand memory, and play a critical role in neuropathological changes in Alzheimer's disease (AD). The in vivocharacterization of nAChRs by positron emission tomography (PET) may increase our understanding of thefunctional implications of these receptors in AD and their early changes during this disease. READ MORE