Search for dissertations about: "cytogenetics"

Showing result 6 - 10 of 78 swedish dissertations containing the word cytogenetics.

  2. 6. Functional analysis of the alpha10beta1 integrin

    Author : Therese Bengtsson; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cytogenetics; Genetik; cytogenetik; limb; gene targeting; chondrocyte; integrin; cartilage;

    Abstract : The aim of this thesis was to study the function of the integrin a10b1. Integrins mediate signals between cells and their environment and regulate several cellular processes such as cell migration, proliferation and differentiation. READ MORE

  4. 7. In vitro and in vivo aspects of intrinsic radiosensitivity

    Author : Karl Brehwens; Andrzej Wojcik; Siamak Haghdoost; Wolfgang Dörr; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radiation biology; changing dose rates; cytogenetics; hypothermia; X-rays; radiotherapy; osteoradionecrosis; biomarkers; oxidative stress; individual radiosensitivity; molekylär biovetenskap; Molecular Biosciences;

    Abstract : This thesis focuses on how physical and biological factors influence the outcome of exposures to γ/X-rays. That the dose rate changes during real life exposure scenarios is well-known, but radiobiological data from exposures performed at increasing or decreasing dose rates is lacking. READ MORE

  5. 8. Characterization of somatic mutations in nonneoplastic cells

    Author : Karin Broberg; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; osteoarthritis; nonneoplastic; HMGIC; trisomy 7; FISH; Molecular genetics; cytogenetics; Klinisk genetik;

    Abstract : Acquired genetic alterations, of which many are visible on the chromosome level, are believed to be necessary for tumorigenesis, and most tumors display characteristic patterns of recurrent structural and numerical aberrations. However, two of the most frequently occurring chromosome mutations in malignant and benign solid tumors, i.e. READ MORE

  6. 9. Evolutionary History of the Root Vole (Microtus oeconomus) as Revealed by Y Chromosome and Mitochondrial DNA sequences

    Author : Cecilia Brunhoff; Malmö Patologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genetics; colonization history; phylogeography; root vole; cytogenetics; Genetik; cytogenetik;

    Abstract : The root vole (Microtus oeconomus) is a rodent with Holarctic distribution. In fact, it is the only Microtus vole found in both Eurasia and North America. Phylogeographic analyses of the root vole from across its distribution range were performed using mitochondrial and Y chromosome DNA sequences. READ MORE

  7. 10. Repetitive DNA in search of a function - a study of telomeric and centromeric sequences in Chironomus

    Author : Casimiro Castillejo-Lopez; Udo Häckers grupp Utvecklingsbiologi i invertebrater; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chironomus; CENP-B box; mobile elements; reverse transcriptase; gene conversion; satellite; repetitive DNA; Telomere; centromere; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Repetitive DNA is quantitatively the main component of telomeres and centromeres, structures responsible for maintenance of the eukaryotic chromosome. The telomere is the specialized nucleoprotein complex that terminates linear chromosomes. READ MORE