Search for dissertations about: "cytogenetik"
Showing result 6 - 10 of 49 swedish dissertations containing the word cytogenetik.
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6. Repetitive DNA in search of a function - a study of telomeric and centromeric sequences in Chironomus
Abstract : Repetitive DNA is quantitatively the main component of telomeres and centromeres, structures responsible for maintenance of the eukaryotic chromosome. The telomere is the specialized nucleoprotein complex that terminates linear chromosomes. READ MORE
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7. The balance between sex and asex: evolutionary genetic studies of reproductive variation in Allium vineale
Abstract : Evolutionary theory predicts a disadvantage to sexual reproduction. This manifests itself either by the higher growth rate of asexual females in a dioecious species, or by the higher transmission rate of a gene conferring asexual female function to its carriers in a hermaphrodite species. READ MORE
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8. Genetic Characterization of Bone and Soft Tissue Tumors
Abstract : Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoints and deletions, and to search for candidate target genes. READ MORE
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9. Development of adenoviral vectors for monitoring telomerase activity in living cells
Abstract : ABSTRACT Telomerase activity is a potential molecular marker for cancer and primitive cells in regenerative tissues. The most commonly used method to measure telomerase activity in cells is the telomerase reverse amplification protocol (TRAP) assay, where the protein extracts derived from homogenized cells are analysed. READ MORE
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10. Laminins and Congenital Muscular Dystrophy - From a Mouse Model to Gene Therapy of Laminin alpha2 chain deficiency?
Abstract : Gene therapy holds great promise for treating many genetic diseases, including muscular dystrophies. Mutations in the gene encoding laminin alpha2 chain ? an extracellular protein prominently expressed in the neuromuscular system ? cause a severe neuromuscular disorder: congenital muscular dystrophy type 1A (MDC1A). READ MORE