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Showing result 1 - 5 of 14 swedish dissertations matching the above criteria.

  2. 1. Human cytokeratins : their use as targets in cancer management

    Author : Birgitta Sundström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cytokeratins, biochemically related to intermediate filaments (IF), form an intracellular network of filaments which contributes to the mechanical stabilizing of the cell. 19 individual polypeptides, divided into two groups, constitute the cytokeratin family. READ MORE

  4. 2. Prognostic factors in colorectal cancer : aspects of tumour dissemination

    Author : Åke Öberg; Gudrun Lindmark; Bengt Jeppsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal neoplasms; prognosis; lymph node metastases; disseminated tumour cells; cytokeratins; micrometastases; metalloproteinases; immune cells; real-time quantitative RT-PCR; carsinoembryonic antigen;

    Abstract : .... READ MORE

  5. 3. Human cytokeratins - their use as targets in cancer management

    Author : Birgitta Sundström; Karlstads universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicin; Biomedical Science; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Abstract : .... READ MORE

  6. 4. Modeling of multi-step oral carcinogenesis in vitro : assessment of growth, differentiation and apoptosis markers

    Author : Annette Hansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Organotypic cultures; apoptosis; terminal squamous differentiation; buccal mucosa; cytokeratins; carcinogenesis; p53;

    Abstract : Human oral mucosa, especially the buccal epithelium, is worldwide a common site for cancer. Cancer development frequently results in inactivation of tumor suppressor p53, a central regulator of growth and programmed cell death, and deregulated expression of structural elements like cytokeratins. READ MORE

  7. 5. A two-dimensional gel electrophoretic study of proteins in tumours of the lung and breast

    Author : Bo Franzén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : gel electrophoresis; protein analysis; sample preparation; mammary tumour; lungcarcinomas; heterogeneity; diagnostic markers.;

    Abstract : Defining differences in gene expression between benign and malignant cells is an important aspectof cancer research, and has been the object of a large number of studies. Such studies are aimed atdefining tumour markers to be used in prognostic studies, and to understand mechanisms leading touncontrolled growth and tumour metastasis. READ MORE